VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy
about
Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regenerationVKORC1 and VKORC1L1: Why do Vertebrates Have Two Vitamin K 2,3-Epoxide Reductases?Structural and functional insights into enzymes of the vitamin K cycleTissue Concentrations of Vitamin K and Expression of Key Enzymes of Vitamin K Metabolism Are Influenced by Sex and Diet but Not Housing in C57Bl6 Mice.GGCX and VKORC1 inhibit osteocalcin endocrine functions.Food Reformulation, Responsive Regulation, and "Regulatory Scaffolding": Strengthening Performance of Salt Reduction Programs in Australia and the United KingdomRecent trends in the metabolism and cell biology of vitamin K with special reference to vitamin K cycling and MK-4 biosynthesis.Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure.Uniparental disomy causes deficiencies of vitamin K-dependent proteins.Phylogeny of the Vitamin K 2,3-Epoxide Reductase (VKOR) Family and Evolutionary Relationship to the Disulfide Bond Formation Protein B (DsbB) Family.Metabolism of vitamin KA mass spectrometry-based proteomic analysis of Homer2-interacting proteins in the mouse brain.Vitamin K and cancer.Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions.VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)Warfarin and vitamin K compete for binding to Phe55 in human VKOR.Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase.Impact of VKORC1, CYP4F2 and NQO1 gene variants on warfarin dose requirement in Han Chinese patients with catheter ablation for atrial fibrillation.Missense mutation of VKORC1 leads to medial arterial calcification in rats
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P2860
VKORC1L1, an enzyme rescuing the vitamin K 2,3-epoxide reductase activity in some extrahepatic tissues during anticoagulation therapy
description
2013 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2013
@ast
im Oktober 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/10/04)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/10/04)
@nl
наукова стаття, опублікована в жовтні 2013
@uk
name
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@ast
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@en
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@nl
type
label
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@ast
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@en
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@nl
prefLabel
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@ast
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@en
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@nl
P2093
P2860
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P1476
VKORC1L1, an enzyme rescuing t ...... during anticoagulation therapy
@en
P2093
Benjamin Matagrin
Etienne Benoit
Gabriele Spohn
Virginie Lattard
P2860
P304
28733-28742
P356
10.1074/JBC.M113.457119
P407
P577
2013-08-08T00:00:00Z