A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activation
about
Targeting protein-protein interactions in complexes organized by A kinase anchoring proteinsThe crystal structure of the RhoA-AKAP-Lbc DH-PH domain complexA-kinase-anchoring protein-Lbc anchors IκB kinase β to support interleukin-6-mediated cardiomyocyte hypertrophyA-kinase anchoring protein Lbc coordinates a p38 activating signaling complex controlling compensatory cardiac hypertrophyIloprost improves endothelial barrier function in lipopolysaccharide-induced lung injury.Stimulation of α1a adrenergic receptors induces cellular proliferation or antiproliferative hypertrophy dependent solely on agonist concentrationThe C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy.AKAPs: the architectural underpinnings of local cAMP signaling.A-kinase anchoring proteins: scaffolding proteins in the heart.The A-kinase-anchoring protein AKAP-Lbc facilitates cardioprotective PKA phosphorylation of Hsp20 on Ser(16).Src homology 2 domain-containing phosphatase 2 (Shp2) is a component of the A-kinase-anchoring protein (AKAP)-Lbc complex and is inhibited by protein kinase A (PKA) under pathological hypertrophic conditions in the heartCreating order from chaos: cellular regulation by kinase anchoring.AKAP signaling complexes: pointing towards the next generation of therapeutic targets?G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function.A-kinase anchoring proteins that regulate cardiac remodeling.PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells.Loss of Protein Kinase Novel 1 (PKN1) is associated with mild systolic and diastolic contractile dysfunction, increased phospholamban Thr17 phosphorylation, and exacerbated ischaemia-reperfusion injury.A-kinase-anchoring protein-Lbc connects stress signaling to cardiac hypertrophy.Common functional variants of the glutamatergic system in Autism spectrum disorder with high and low intellectual abilities.A-Kinase Anchoring Protein-Lbc: A Molecular Scaffold Involved in Cardiac Protection.Noradrenaline enhances angiotensin II responses via p38 MAPK activation after hypoxia/re-oxygenation in renal interlobar arteries.
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P2860
A-kinase anchoring protein (AKAP)-Lbc anchors a PKN-based signaling complex involved in α1-adrenergic receptor-induced p38 activation
description
2011 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2011
@ast
im März 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/03/11)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/03/11)
@nl
наукова стаття, опублікована в березні 2011
@uk
name
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@ast
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@en
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@nl
type
label
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@ast
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@en
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@nl
prefLabel
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@ast
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@en
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@nl
P2093
P2860
P921
P356
P1476
A-kinase anchoring protein (AK ...... eceptor-induced p38 activation
@en
P2093
Dario Diviani
Luca Cariolato
Sabrina Cavin
P2860
P304
P356
10.1074/JBC.M110.185645
P407
P577
2011-03-11T00:00:00Z