STAT2 deficiency and susceptibility to viral illness in humans
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Viral Inhibition of the IFN-Induced JAK/STAT Signalling Pathway: Development of Live Attenuated Vaccines by Mutation of Viral-Encoded IFN-AntagonistsNatural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse CytomegalovirusHuman IFNAR2 deficiency: Lessons for antiviral immunitySignal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fissionHuman TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndromeNLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.Guidelines for genetic studies in single patients: lessons from primary immunodeficiencies.DNA polymerase-α regulates the activation of type I interferons through cytosolic RNA:DNA synthesisHuman Cytomegalovirus Immediate-Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6-Type to an IFNγ-Like ResponseSTAT2 Is a Pervasive Cytokine Regulator due to Its Inhibition of STAT1 in Multiple Signaling PathwaysThe Ying and Yang of STAT3 in Human DiseaseSTAT5B deficiency: Impacts on human growth and immunitySTAT2 Is Required for TLR-Induced Murine Dendritic Cell Activation and Cross-PresentationSTAT2 phosphorylation and signaling.The JAK-STAT pathway: impact on human disease and therapeutic interventionSTAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling.Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.JAK-STAT Signaling as a Target for Inflammatory and Autoimmune Diseases: Current and Future Prospects.Autoimmunity and Primary Immunodeficiency Disorders.The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus.The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung.RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies.The Essential Role of Type I Interferons in Differentiation and Activation of Tumor-Associated Neutrophils.Within host RNA virus persistence: mechanisms and consequences.Emerging Infections and Pertinent Infections Related to Travel for Patients with Primary Immunodeficiencies.Type I Interferons in Newborns-Neurotoxicity versus Antiviral Defense.Gone fission: an asymptomatic STAT2 mutation elongates mitochondria and causes human disease following viral infection.Modular cell-based platform for high throughput identification of compounds that inhibit a viral interferon antagonist of choice.A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations.Type I interferon-regulated gene expression and signaling in murine mixed glial cells lacking signal transducers and activators of transcription 1 or 2 or interferon regulatory factor 9.A systematic approach to the development of a safe live attenuated Zika vaccine.Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis.Laboratory evaluation of the IFN-γ circuit for the molecular diagnosis of Mendelian susceptibility to mycobacterial disease.STAT2-dependent immune responses ensure host survival despite the presence of a potent viral antagonist.A Positive Feedback Amplifier Circuit That Regulates Interferon (IFN)-Stimulated Gene Expression and Controls Type I and Type II IFN Responses.Dominant-negative STAT5B mutations cause growth hormone insensitivity with short stature and mild immune dysregulation.
P2860
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P2860
STAT2 deficiency and susceptibility to viral illness in humans
description
2013 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2013
@ast
im Februar 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/02/19)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/02/19)
@nl
наукова стаття, опублікована в лютому 2013
@uk
name
STAT2 deficiency and susceptibility to viral illness in humans
@ast
STAT2 deficiency and susceptibility to viral illness in humans
@en
STAT2 deficiency and susceptibility to viral illness in humans
@nl
type
label
STAT2 deficiency and susceptibility to viral illness in humans
@ast
STAT2 deficiency and susceptibility to viral illness in humans
@en
STAT2 deficiency and susceptibility to viral illness in humans
@nl
prefLabel
STAT2 deficiency and susceptibility to viral illness in humans
@ast
STAT2 deficiency and susceptibility to viral illness in humans
@en
STAT2 deficiency and susceptibility to viral illness in humans
@nl
P2093
P2860
P50
P3181
P356
P1476
STAT2 deficiency and susceptibility to viral illness in humans
@en
P2093
Andrew J Cant
Dan F Young
Manoj Valappil
Paul Dickinson
Scott J Hackett
Siti M B Mohamad
Sophie Hambleton
P2860
P304
P3181
P356
10.1073/PNAS.1220098110
P407
P577
2013-02-07T00:00:00Z