Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
about
TIM-3 Regulates Distinct Functions in MacrophagesDisruption of a Regulatory Network Consisting of Neutrophils and Platelets Fosters Persisting Inflammation in Rheumatic DiseasesNK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?Involvement of HMGB1 in Resistance to Tumor Vessel-Targeted, Monoclonal Antibody-Based ImmunotherapyPhosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancerRole of Tim-3 in hepatitis B virus infection: An overviewConcepts and mechanisms underlying chemotherapy induced immunogenic cell death: impact on clinical studies and considerations for combined therapiesModulation of APC Function and Anti-Tumor Immunity by Anti-Cancer DrugsThe Role of HMGB1 Signaling Pathway in the Development and Progression of Hepatocellular Carcinoma: A ReviewBeyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint RegulatorsPrognostic and Predictive Value of DAMPs and DAMP-Associated Processes in CancerThe Tumor Macroenvironment: Cancer-Promoting Networks Beyond Tumor BedsTim-3 and Tim-4 as the potential targets for antitumor therapyCross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell SubsetsTumor-infiltrating dendritic cells in cancer pathogenesisBlocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune responseDendritic cell-targeted approaches to modulate immune dysfunction in the tumor microenvironmentMetabolic influences that regulate dendritic cell function in tumorsDAMPs, MAMPs, and NAMPs in plant innate immunityDamage-associated molecular patterns in cancer: a double-edged swordContribution of dendritic cells to the autoimmune pathology of systemic lupus erythematosusTIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling PathwayThe dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunityMelanoma-infiltrating dendritic cells: Limitations and opportunities of mouse modelsTim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infectionRole of TIM-3 in ovarian cancer.Liver-primed CD8+ T cells suppress antiviral adaptive immunity through galectin-9-independent T-cell immunoglobulin and mucin 3 engagement of high-mobility group box 1 in mice.The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxiaCheckpoint inhibitors in hematological malignanciesPlasma Levels of High-Mobility Group Box 1 during Peptide Vaccination in Patients with Recurrent Ovarian Cancer.Emerging role of HMGB1 in lung diseases: friend or foe.RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expressionVariability in CRP, regulatory T cells and effector T cells over time in gynaecological cancer patients: a study of potential oscillatory behaviour and correlationsTim-3 and its role in regulating anti-tumor immunity.Increased plasma cell-free DNA level during HTNV infection: correlation with disease severity and virus load.Regulation of T cell responses by the receptor molecule Tim-3.Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaquesHMGB1 in health and disease.Tim-3 protects decidual stromal cells from toll-like receptor-mediated apoptosis and inflammatory reactions and promotes Th2 bias at the maternal-fetal interface.Up-regulation of Tim-3 on T cells during acute simian immunodeficiency virus infection and on antigen specific responders.
P2860
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P2860
Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1
description
2012 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im September 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/09/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/09/01)
@nl
наукова стаття, опублікована у вересні 2012
@uk
مقالة علمية (نشرت في سبتمبر 2012)
@ar
name
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@ast
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@en
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@nl
type
label
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@ast
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@en
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@nl
prefLabel
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@ast
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@en
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Tumor-infiltrating DCs suppres ...... or TIM-3 and the alarmin HMGB1
@en
P2093
Akinori Takaoka
Hideo Yagita
Hirotoshi Dosaka-Akita
Hisaya Akiba
Ichiro Kinoshita
Jacob V Gorman
Masahisa Jinushi
Mitsuomi Hirashima
Shigeki Chiba
Toshimitsu Uede
P2860
P304
P3181
P356
10.1038/NI.2376
P407
P577
2012-07-29T00:00:00Z