Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

Item
http://www.wikidata.org/entity/Q28138216
Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PDInhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1Squamous cell carcinoma antigen 1-mediated binding of hepatitis B virus to hepatocytes does not involve the hepatic serpin clearance systemThe squamous cell carcinoma antigen 2 inhibits the cysteine proteinase activity of a major mite allergen, Der p 1Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.Development of recombinant inhibitors specific to human kallikrein 2 using phage-display selected substrates.Adaptive evolution and divergence of SERPINB3: a young duplicate in great Apes.SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change.Evolution of placental proteases.Multiple domains of endopin 2A for serpin cross-class inhibition of papain.Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.Conditionally replicating E1B-deleted adenovirus driven by the squamous cell carcinoma antigen 2 promoter for uterine cervical cancer therapy.The Spn4 gene from Drosophila melanogaster is a multipurpose defence tool directed against proteases from three different peptidase families.SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target.
P2860

Simple modifications of the serpin reactive site loop convert SCCA2 into a cysteine proteinase inhibitor: a critical role for the P3' proline in facilitating RSL cleavage

Item
http://www.wikidata.org/entity/Q28138216
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Simple modifications of the se ...... e in facilitating RSL cleavage
@ast
Simple modifications of the se ...... e in facilitating RSL cleavage
@en
Simple modifications of the se ...... e in facilitating RSL cleavage
@nl
type
label
Simple modifications of the se ...... e in facilitating RSL cleavage
@ast
Simple modifications of the se ...... e in facilitating RSL cleavage
@en
Simple modifications of the se ...... e in facilitating RSL cleavage
@nl
prefLabel
Simple modifications of the se ...... e in facilitating RSL cleavage
@ast
Simple modifications of the se ...... e in facilitating RSL cleavage
@en
Simple modifications of the se ...... e in facilitating RSL cleavage
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Simple modifications of the se ...... e in facilitating RSL cleavage
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698