CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70 - Test2 - elhamkhani - TriplyDB

CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70

CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70

http://www.wikidata.org/entity/Q28138256

about

The nucleotide exchange factors of Hsp70 molecular chaperones A Role for the Chaperone Complex BAG3-HSPB8 in Actin Dynamics, Spindle Orientation and Proper Chromosome Segregation during Mitosis BAG4/SODD protein contains a short BAG domain BAG3: a new player in the heart failure paradigm Molecular chaperone targeting and regulation by BAG family proteins BAG3 protein controls B-chronic lymphocytic leukaemia cell apoptosis Regulation by heavy metals and temperature of the human BAG-3 gene, a modulator of Hsp70 activity CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins The anti-apoptotic protein BAG-3 is overexpressed in pancreatic cancer and induced by heat stress in pancreatic cancer cell lines BAG3 protein is overexpressed in human glioblastoma and is a potential target for therapy BAG3 deficiency results in fulminant myopathy and early lethality Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro Hsp70-Bag3 interactions regulate cancer-related signaling networks Structural basis for recognition of the T cell adaptor protein SLP-76 by the SH3 domain of phospholipase Cgamma1 HSPA8/HSC70 chaperone protein: structure, function, and chemical targeting.Bag3-induced autophagy is associated with degradation of JCV oncoprotein, T-Ag.Roles of PLC-gamma2 and PKCalpha in TPA-induced apoptosis of gastric cancer cells The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome.IKK{gamma} protein is a target of BAG3 regulatory activity in human tumor growth.BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity.Getting folded: chaperone proteins in muscle development, maintenance and disease.Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9 Bis is Induced by Oxidative Stress via Activation of HSF1 Identification of extracellular signal-regulated kinase 1 (ERK1) direct substrates using stable isotope labeled kinase assay-linked phosphoproteomics.Drosophila starvin encodes a tissue-specific BAG-domain protein required for larval food uptake.BAG3 expression in glioblastoma cells promotes accumulation of ubiquitinated clients in an Hsp70-dependent manner.BAG3 regulates formation of the SNARE complex and insulin secretion BAG-1--a nucleotide exchange factor of Hsc70 with multiple cellular functions.Cordyceps sinensis attenuates renal fibrosis and suppresses BAG3 induction in obstructed rat kidney BAG3 regulates ECM accumulation in renal proximal tubular cells induced by TGF-β1.Heat shock protein 70 regulates platelet integrin activation, granule secretion and aggregation.BAG3-dependent noncanonical autophagy induced by proteasome inhibition in HepG2 cells Implication of Bcl-2-associated athanogene 3 in fibroblast growth factor-2-mediated epithelial-mesenchymal transition in renal epithelial cells.Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity.ERK-mediated phosphorylation of BIS regulates nuclear translocation of HSF1 under oxidative stress.Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors.Correlation of BAG-3 and heat shock protein 70 with CD30 expression in T-cell lymphomas.Knockdown of BAG3 induces epithelial-mesenchymal transition in thyroid cancer cells through ZEB1 activation.Molecular chaperones as rational drug targets for Parkinson's disease therapeutics.Hsp70 in cancer: back to the future.

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CAIR-1/BAG-3 forms an EGF-regulated ternary complex with phospholipase C-gamma and Hsp70/Hsc70

http://www.wikidata.org/entity/Q28138256

description

2000 nî lūn-bûn

@nan

2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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CAIR-1/BAG-3 forms an EGF-regu ...... lipase C-gamma and Hsp70/Hsc70

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C Gasbarre

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E Kohn

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H Doong

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L A Liotta

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An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators

Bis, a Bcl-2-binding protein that synergizes with Bcl-2 in preventing cell death

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

SH2 and SH3 domains: elements that control interactions of cytoplasmic signaling proteins

Signaling through scaffold, anchoring, and adaptor proteins

Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity

The Hsp70 and Hsp60 chaperone machines

Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

SH2/SH3 signaling proteins.

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4385-95

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scholarly article

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3372227

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10.1038/SJ.ONC.1203797

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38

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19

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2000-09-07T00:00:00Z

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12340890

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1042695074

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10980614

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