The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
about
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanismsThe tripartite motif family identifies cell compartments.Nucleocytoplasmic shuttling of endocytic proteinsEarly endosomal regulation of Smad-dependent signaling in endothelial cellsNovel rab GAP-like protein, CIP85, interacts with connexin43 and induces its degradationThe TRE17 oncogene encodes a component of a novel effector pathway for Rho GTPases Cdc42 and Rac1 and stimulates actin remodelingScreening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activityStructural basis of Rab5-Rabaptin5 interaction in endocytosisSpecific Rab GTPase-activating proteins define the Shiga toxin and epidermal growth factor uptake pathwaysThe TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6.The tumor susceptibility gene TMEM127 is mutated in renal cell carcinomas and modulates endolysosomal functionCell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval developmentProteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles.AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase-activating protein domainGrit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter moleculesA comprehensive pathway map of epidermal growth factor receptor signalingAmyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid raftsEndosome maturationThe Evi5 family in cellular physiology and pathologyFunction and regulation of the endosomal fusion and fission machineriesGTPase networks in membrane trafficDevelopmentally regulated GTP-binding protein 2 coordinates Rab5 activity and transferrin recycling.Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells.Molecular basis for the dual function of Eps8 on actin dynamics: bundling and cappingIdentification of EPI64 as a GTPase-activating protein specific for Rab27ARegulation of epidermal growth factor receptor endocytosis by wortmannin through activation of Rab5 rather than inhibition of phosphatidylinositol 3-kinase.Novel binding partners and differentially regulated phosphorylation sites clarify Eps8 as a multi-functional adaptorRegulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Alsin is a Rab5 and Rac1 guanine nucleotide exchange factorEndocytosis-dominated membrane area decrease requires Rab5 protein in rat melanotrophsThe activity of the GTPase-activating protein CdGAP is regulated by the endocytic protein intersectinThe signaling adaptor Eps8 is an essential actin capping protein for dendritic cell migrationThe connexin43-interacting protein, CIP85, mediates the internalization of connexin43 from the plasma membrane.An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligandEndocytosis of epidermal growth factor receptor regulated by Grb2-mediated recruitment of the Rab5 GTPase-activating protein RN-tre.Phagosome maturation: going through the acid testPhosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms.Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.Regulation of endosomal motility and degradation by amyotrophic lateral sclerosis 2/alsin.Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells
P2860
Q21146412-DD078039-32C5-47BA-9FC3-6ED79F2D31D6Q24291183-B12090FE-AAA1-4E1C-80E0-3612C921289CQ24291367-D505AA88-5E0B-495C-8746-F7DC1731C123Q24292399-B0540F6C-066A-48E9-A0DC-5E3F6641CC0CQ24294859-AD774942-4711-47FA-8484-9D02170A5D70Q24296635-771CDBD4-70F4-4B8C-8B95-D38EEC8A1ED9Q24300416-450C7092-86D8-4A38-B0ED-258248502A33Q24304419-5C5C518E-EB52-4696-B608-9112B9ACE01BQ24309468-5287226B-FF73-4457-9B4E-8BE1098614ACQ24309600-C2DDDB70-1273-470A-A22A-EAB70BB47C03Q24312781-EC54843F-74F4-4B5E-9EF6-B4BAB9FDC485Q24336986-10FD787F-9BDF-492D-8382-607AD18A8B6DQ24339459-D7AD0264-15C1-468A-B8AD-415F93D395AEQ24536241-EE223880-E10B-4084-A64C-1A1E0DFC3A10Q24540188-64A863A1-CC19-4550-9B1F-BBE794101D9EQ24672490-9EBAFA77-54C0-4440-B534-02B4DEC0E54DQ24675729-BD2E9AF0-6681-417F-9044-5CA2B8E7725CQ26992067-F086097C-DE43-4EEF-BEF1-832D1BF2878EQ27013381-67B29C80-9217-4735-930E-109029D76627Q27015677-88A5D38F-9900-4F82-82F8-456B925F89EEQ27015776-05D07C57-A354-408E-A093-4A7FBE7AC1E8Q27305184-FACE4DD7-3A5D-43B0-85C5-083600253C9FQ27321482-9B5CEE72-64E3-476B-8986-4775D19EDCADQ27324384-23CD2909-69E7-4C74-89D8-6BE49200F8D3Q28259174-5665593C-9F05-4384-88C0-4607E8193F7FQ28353898-BE604A60-D5E3-4942-B014-63A31D516C11Q28486658-61ADF740-A748-472F-A9C9-AFE09278997AQ28504869-9A228700-F496-4527-8A0C-F865396FD0B2Q28509300-427A1C45-7C8E-4DA5-ADE7-688944A9525DQ28575096-12EDDA87-C6F9-45BD-BA02-2509E9AA53E1Q28589410-7CF99096-0B15-49FB-8395-652A55700F02Q28589982-135FF0DC-8594-4A44-85AA-6BD85094DA1CQ30009876-BCE2E147-F4A3-4917-9B55-46CF5929ACBBQ30159794-6C1AEB70-D426-4914-B13D-CDFC1CF0A522Q30165133-2A9A6295-7753-4FC5-98DD-827A6A02C3D7Q30435417-6CA18AE0-9D87-410C-B901-68A0B7070AFEQ30478070-5DE9288E-57F0-44BB-A778-616480E84A2CQ30480364-1FB33F88-7BA9-494A-964E-2B656DA6A1E5Q30489444-D4E40E76-9198-46A6-B01B-66966DA256A1Q30617877-1F2AEAF6-B9E3-4DAB-8D42-177604EAC48C
P2860
The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@ast
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@en
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@nl
type
label
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@ast
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@en
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@nl
prefLabel
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@ast
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@en
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@nl
P2093
P2860
P356
P1433
P1476
The Eps8 protein coordinates E ...... c and trafficking through Rab5
@en
P2093
L Lanzetti
M G Malabarba
P P Di Fiore
S Christoforidis
P2860
P2888
P356
10.1038/35042605
P407
P577
2000-11-16T00:00:00Z
P6179
1045013642