The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family
about
Wnt/β-catenin signaling in kidney injury and repair: a double-edged swordMitochondrial and nuclear forms of Wnt13 are generated via alternative promoters, alternative RNA splicing, and alternative translation start sitesThe p53 transcriptional target gene wnt7b contributes to NGF-inducible neurite outgrowth in neuronal PC12 cellsSmall molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancerDifferential use of signal peptides and membrane domains is a common occurrence in the protein output of transcriptional units.Gene expression profiling in cells with enhanced gamma-secretase activity.ABC transporters in CSCs membranes as a novel target for treating tumor relapse.Phenotypic annotation of the mouse X chromosomeBlockade to pathological remodeling of infarcted heart tissue using a porcupine antagonistDifferential palmit(e)oylation of Wnt1 on C93 and S224 residues has overlapping and distinct consequences.Concentration-dependent effects of WNTLESS on WNT1/3A signaling.Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)PORCN moonlights in a Wnt-independent pathway that regulates cancer cell proliferationUpdating the Wnt pathways.Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia.Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesisPorcupine is not required for the production of the majority of Wnts from primary human astrocytes and CD8+ T cellsDeletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndromeNucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signalingPrecise regulation of porcupine activity is required for physiological Wnt signaling.Lung disease recalling paraseptal emphysema in a patient with Goltz syndrome.Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury.Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins.Acyltransferases for secreted signalling proteins (Review).Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development.LPS-induced inflammatory response is suppressed by Wnt inhibitors, Dickkopf-1 and LGK974Dissecting the Wnt secretion pathway: key questions on the modification and intracellular trafficking of Wnt proteins.Wntless in Wnt secretion: molecular, cellular and genetic aspects.Interaction of sonic hedgehog (SHH) pathway with cancer stem cell genes in gastric cancer.p24 family proteins: key players in the regulation of trafficking along the secretory pathway.Vertebrate Axial Patterning: From Egg to Asymmetry.Wnt/β-catenin signaling plays an ever-expanding role in stem cell self-renewal, tumorigenesis and cancer chemoresistance.Drosophila wnt-1 undergoes a hydrophobic modification and is targeted to lipid rafts, a process that requires porcupine.Divergent effects of Porcupine and Wntless on WNT1 trafficking, secretion, and signaling.Identification of the WNT1 residues required for palmitoylation by Porcupine.Drosophila segment polarity gene product porcupine stimulates the posttranslational N-glycosylation of wingless in the endoplasmic reticulum.Wnt/β-catenin signaling during early vertebrate neural development.Biochemical Methods to Analyze Wnt Protein Secretion.Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia.
P2860
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P2860
The evolutionarily conserved porcupine gene family is involved in the processing of the Wnt family
description
2000 nî lūn-bûn
@nan
2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The evolutionarily conserved p ...... e processing of the Wnt family
@ast
The evolutionarily conserved p ...... e processing of the Wnt family
@en
The evolutionarily conserved p ...... e processing of the Wnt family
@nl
type
label
The evolutionarily conserved p ...... e processing of the Wnt family
@ast
The evolutionarily conserved p ...... e processing of the Wnt family
@en
The evolutionarily conserved p ...... e processing of the Wnt family
@nl
prefLabel
The evolutionarily conserved p ...... e processing of the Wnt family
@ast
The evolutionarily conserved p ...... e processing of the Wnt family
@en
The evolutionarily conserved p ...... e processing of the Wnt family
@nl
P2093
P2860
P921
P3181
P1433
P1476
The evolutionarily conserved p ...... e processing of the Wnt family
@en
P2093
K Okabayashi
M Asashima
N Perrimon
T Kadowaki
P2860
P304
P3181
P356
10.1046/J.1432-1033.2000.01478.X
P407
P577
2000-07-01T00:00:00Z