Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor
about
Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperoneCaveolin-1 and -2 in airway epithelium: expression and in situ association as detected by FRET-CLSMNitrosation-dependent caveolin 1 phosphorylation, ubiquitination, and degradation and its association with idiopathic pulmonary arterial hypertensionInhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescenceTLP, a novel modulator of TGF-beta signaling, has opposite effects on Smad2- and Smad3-dependent signalingAutophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironmentKetones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolismThe autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolismOxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cellsAn absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancersEnzyme replacement reverses abnormal cerebrovascular responses in Fabry diseaseAssembly and Turnover of Caveolae: What Do We Really Know?Endothelial to Mesenchymal Transition (EndoMT) in the Pathogenesis of Human Fibrotic DiseasesStudying GPCR/cAMP pharmacology from the perspective of cellular structureCurrent concepts on primary open-angle glaucoma genetics: a contribution to disease pathophysiology and future treatmentNeurogenic inflammation after traumatic brain injury and its potentiation of classical inflammationSyntenin regulates TGF-β1-induced Smad activation and the epithelial-to-mesenchymal transition by inhibiting caveolin-mediated TGF-β type I receptor internalizationPulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolaseCaveolin-1 knockout mice exhibit airway hyperreactivityAnimal models of systemic sclerosis: their utility and limitations.Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-β in endothelial cellsSeparation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functionsSonic hedgehog ligand partners with caveolin-1 for intracellular transportPituitary adenylate cyclase-activating polypeptide induces translocation of its G-protein-coupled receptor into caveolin-enriched membrane microdomains, leading to enhanced cyclic AMP generation and neurite outgrowth in PC12 cellsInactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in miceRegistered report: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasisSDPR induces membrane curvature and functions in the formation of caveolae.Different domains regulate homomeric and heteromeric complex formation among type I and type II transforming growth factor-beta receptors.Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo.Muscular atrophy of caveolin-3-deficient mice is rescued by myostatin inhibition.Plasma membrane domain organization regulates EGFR signaling in tumor cellsLive-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane.Dynamic caveolae exclude bulk membrane proteins and are required for sorting of excess glycosphingolipids.Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis.Riding shotgun: a dual role for the epidermal growth factor-Cripto/FRL-1/Cryptic protein Cripto in Nodal trafficking.HIV-1 stimulates nuclear entry of amyloid beta via dynamin dependent EEA1 and TGF-β/Smad signaling.Aberrant caveolin-1-mediated Smad signaling and proliferation identified by analysis of adenine 474 deletion mutation (c.474delA) in patient fibroblasts: a new perspective on the mechanism of pulmonary hypertension.Cavin-3 (PRKCDBP) deficiency reduces the density of caveolae in smooth muscle.Molecular and functional characterization of the BMPR2 gene in Pulmonary Arterial HypertensionEndothelial cells isolated from caveolin-2 knockout mice display higher proliferation rate and cell cycle progression relative to their wild-type counterparts
P2860
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P2860
Caveolin-1 regulates transforming growth factor (TGF)-beta/SMAD signaling through an interaction with the TGF-beta type I receptor
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@ast
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@en
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@nl
type
label
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@ast
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@en
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@nl
prefLabel
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@ast
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@en
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@nl
P2093
P3181
P356
P1476
Caveolin-1 regulates transform ...... h the TGF-beta type I receptor
@en
P2093
E P Böttinger
G von Gersdorff
M P Lisanti
P304
P3181
P356
10.1074/JBC.M008340200
P407
P577
2001-03-02T00:00:00Z