Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
about
Characterization of TASK-4, a novel member of the pH-sensitive, two-pore domain potassium channel familyRegulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genisteinGeneral anesthesia mediated by effects on ion channelsModulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of actionBlock of the background K(+) channel TASK-1 contributes to arrhythmogenic effects of platelet-activating factorThe acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking.Localization of TASK and TREK, two-pore domain K+ channels, in human cytotrophoblast cellsKcnkø: single, cloned potassium leak channels are multi-ion poresAdenosine stimulates depolarization and rise in cytoplasmic [Ca2+] in type I cells of rat carotid bodiesPituitary adenylate cyclase-activating polypeptide (PACAP) stimulates the oxygen sensing type I (glomus) cells of rat carotid bodies via reduction of a background TASK-like K+ currentConvergent and reciprocal modulation of a leak K+ current and I(h) by an inhalational anaesthetic and neurotransmitters in rat brainstem motoneurones.SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.Membrane potential depolarization as a triggering mechanism for Vpu-mediated HIV-1 release.Transmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.A high-throughput functional screen identifies small molecule regulators of temperature- and mechano-sensitive K2P channels.Molecular aspects of structure, gating, and physiology of pH-sensitive background K2P and Kir K+-transport channels.Two-pore-Domain (KCNK) potassium channels: dynamic roles in neuronal function.Carvedilol targets human K2P 3.1 (TASK1) K+ leak channelsThe Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9.Substance P Depolarizes Lamprey Spinal Cord Neurons by Inhibiting Background Potassium Channels.TASK1 (K(2P)3.1) K(+) channel inhibition by endothelin-1 is mediated through Rho kinase-dependent phosphorylationMetabolic and thermal stimuli control K(2P)2.1 (TREK-1) through modular sensory and gating domains.Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics.Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidificationProtons block BK channels by competitive inhibition with K+ and contribute to the limits of unitary currents at high voltages.Opening and closing of KCNKO potassium leak channels is tightly regulated.Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors.The selectivity, voltage-dependence and acid sensitivity of the tandem pore potassium channel TASK-1: contributions of the pore domains.A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics.Proton inhibition of unitary currents of vanilloid receptors.Potassium channels in peripheral pain pathways: expression, function and therapeutic potential.Gating of two pore domain potassium channels.TREK-1 K(+) channels in the cardiovascular system: their significance and potential as a therapeutic target.A Role for K2P Channels in the Operation of Somatosensory NociceptorsK(+) channels: function-structural overview.The role of acid-sensitive two-pore domain potassium channels in cardiac electrophysiology: focus on arrhythmias.The family of K2P channels: salient structural and functional properties.TASK channels in arterial chemoreceptors and their role in oxygen and acid sensing.Much more than a leak: structure and function of K₂p-channels.Gating, Regulation, and Structure in K2P K+ Channels: In Varietate Concordia?
P2860
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P2860
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@ast
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@en
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@nl
type
label
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@ast
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@en
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@nl
prefLabel
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@ast
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@en
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@nl
P2093
P2860
P356
P1476
Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3
@en
P2093
M H Butler
P G Gallagher
S A Goldstein
P2860
P304
P356
10.1074/JBC.M001948200
P407
P577
2000-06-02T00:00:00Z