Transcriptional repression of the E2F-1 gene by interferon-alpha is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes
about
Control of cell cycle exit and entry by protein kinase B-regulated forkhead transcription factorsDeregulated E2F transcriptional activity in autonomously growing melanoma cellsPhosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.Differences in E2F subunit expression in quiescent and proliferating vascular smooth muscle cellsBcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein-ubiquitin ligase SCF(Skp2).Cul7/p185/p193 binding to simian virus 40 large T antigen has a role in cellular transformation.Cardiac myocyte cell cycle control in development, disease, and regeneration.Cell-context specific role of the E2F/Rb pathway in development and disease.Type I interferons induce apoptosis by balancing cFLIP and caspase-8 independent of death ligands.E2F4 plays a key role in Burkitt lymphoma tumorigenesis.Nuclear expression of E2F4 induces cell death via multiple pathways in normal human intestinal epithelial crypt cells but not in colon cancer cells.Apaf-1 is a mediator of E2F-1-induced apoptosis.An E2F-binding site mediates the activation of the proliferative isoform of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase by phosphatidylinositol 3-kinaseMullerian inhibiting substance inhibits ovarian cell growth through an Rb-independent mechanism.IFN-α inhibits telomerase in human CD8⁺ T cells by both hTERT downregulation and induction of p38 MAPK signaling.Overlapping roles of pocket proteins in the myocardium are unmasked by germ line deletion of p130 plus heart-specific deletion of Rb.A B-myb promoter corepressor site facilitates in vivo occupation of the adjacent E2F site by p107 x E2F and p130 x E2F complexes.The nucleocytoplasmic shuttling of E2F4 is involved in the regulation of human intestinal epithelial cell proliferation and differentiation.Phosphorylation of the retinoblastoma-related protein p130 in growth-arrested cells.
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P2860
Transcriptional repression of the E2F-1 gene by interferon-alpha is mediated through induction of E2F-4/pRB and E2F-4/p130 complexes
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@ast
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@en
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@nl
type
label
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@ast
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@en
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@nl
prefLabel
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@ast
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@en
Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@nl
P2093
P2860
P356
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Transcriptional repression of ...... 4/pRB and E2F-4/p130 complexes
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202500
P407
P577
1999-03-18T00:00:00Z
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P6179
1013036409