Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2 - Test2 - elhamkhani - TriplyDB

Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2

Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2

http://www.wikidata.org/entity/Q28143997

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Role of the pleckstrin homology domain of PLCgamma1 in its interaction with the insulin receptor The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta Candidate genes for testicular cancer evaluated by in situ protein expression analyses on tissue microarrays Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins Structural basis for dimerization of the Grb10 Src homology 2 domain. Implications for ligand specificity The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver Regulation of stress granule dynamics by Grb7 and FAK signalling pathway The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling Distinct recruitment and function of Gab1 and Gab2 in Met receptor-mediated epithelial morphogenesis.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Novel nonphosphorylated peptides with conserved sequences selectively bind to Grb7 SH2 domain with affinity comparable to its phosphorylated ligand.The testicular germ cell tumour genome.Grb10 and Grb14: enigmatic regulators of insulin action--and more?Adapter protein connections: the MRL and Grb7 protein families.Dissecting GRB7-mediated signals for proliferation and migration in HER2 overexpressing breast tumor cells: GTP-ase rules.Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis Inputs and outputs of insulin receptor.The cancer-associated FGFR4-G388R polymorphism enhances pancreatic insulin secretion and modifies the risk of diabetes.Growth factor receptor-binding protein 10 (Grb10) as a partner of phosphatidylinositol 3-kinase in metabolic insulin action.Grb7 and Hax1 may colocalize partially to mitochondria in EGF-treated SKBR3 cells and their interaction can affect Caspase3 cleavage of Hax1 Adaptor signalling proteins Grb2 and Grb7 are recruited by human G6f, a novel member of the immunoglobulin superfamily encoded in the MHC.The BPS domain of Grb10 inhibits the catalytic activity of the insulin and IGF1 receptors.Inhibition of FGF receptor signalling in Xenopus oocytes: differential effect of Grb7, Grb10 and Grb14.

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Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2

http://www.wikidata.org/entity/Q28143997

description

2000 nî lūn-bûn

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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի ապրիլին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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Evidence for an interaction be ...... s binding domains, PIR and SH2

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Evidence for an interaction be ...... s binding domains, PIR and SH2

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Evidence for an interaction be ...... s binding domains, PIR and SH2

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A F Burnol

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A Kasus-Jacobi

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D Perdereau

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P2860

Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose

Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains

Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2

Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

A novel variant of human Grb7 is associated with invasive esophageal carcinoma

Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis

Grb-IR: a SH2-domain-containing protein that binds to the insulin receptor and inhibits its function

High-efficiency expression/cloning of epidermal growth factor-receptor-binding proteins with Src homology 2 domains

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2052-9

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10.1038/SJ.ONC.1203469

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1039859817

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