Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway - Test2 - elhamkhani - TriplyDB

Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

http://www.wikidata.org/entity/Q28144297

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Oligomerization of optineurin and its oxidative stress- or E50K mutation-driven covalent cross-linking: possible relationship with glaucoma pathology Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection NEMO specifically recognizes K63-linked poly-ubiquitin chains through a new bipartite ubiquitin-binding domain Interaction between optineurin and the bZIP transcription factor NRL Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.Posttranslational modifications, localization, and protein interactions of optineurin, the product of a glaucoma gene NEMO trimerizes through its coiled-coil C-terminal domain Processing of optineurin in neuronal cells Structure-function analysis of the A20-binding inhibitor of NF-kappa B activation, ABIN-1 M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells The TBK1-binding domain of optineurin promotes type I interferon responses A novel amyotrophic lateral sclerosis mutation in OPTN induces ER stress and Golgi fragmentation in vitro.Mutations of optineurin in amyotrophic lateral sclerosis Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant.NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.Impairment of protein trafficking upon overexpression and mutation of optineurin.Studies of optineurin, a glaucoma gene: Golgi fragmentation and cell death from overexpression of wild-type and mutant optineurin in two ocular cell types.Induction of autophagy in rats upon overexpression of wild-type and mutant optineurin gene.Functions and mechanisms of action of the adenovirus E3 proteins.Optineurin regulates the interferon response in a cell cycle-dependent manner Cellular and molecular biology of optineurin.Myocilin and Optineurin: Differential Characteristics and Functional Consequences Optineurin insufficiency impairs IRF3 but not NF-κB activation in immune cells.Effects of mutations and deletions in the human optineurin gene.Toward an integrative view of Optineurin functions.Optineurin increases cell survival and translocates to the nucleus in a Rab8-dependent manner upon an apoptotic stimulus.Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.Optineurin associates with the podocyte Golgi complex to maintain its structure.Overexpressed mutant optineurin(E50K) induces retinal ganglion cells apoptosis via the mitochondrial pathway.Inhibition of NF-kappa B activation by peptides targeting NF-kappa B essential modulator (nemo) oligomerization.Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.Expression of optineurin isolated from rat-injured dental pulp and the effects on inflammatory signals in normal rat kidney cells.Inducible turnover of optineurin regulates T cell activation.Oligogenic inheritance of optineurin (OPTN) and C9ORF72 mutations in ALS highlights localisation of OPTN in the TDP-43-negative inclusions of C9ORF72-ALS.Optineurin Functions for Optimal Immunity.Transgenic mice with overexpression of mutated human optineurin(E50K) in the retina.Optineurin: A Coordinator of Membrane-Associated Cargo Trafficking and Autophagy.

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Phorbol esters and cytokines regulate the expression of the NEMO-related protein, a molecule involved in a NF-kappa B-independent pathway

http://www.wikidata.org/entity/Q28144297

description

2000 nî lūn-bûn

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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2000 թվականի հուլիսին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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2000年论文

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name

Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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type

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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prefLabel

Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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Phorbol esters and cytokines r ...... NF-kappa B-independent pathway

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P2093

A Israël

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G Courtois

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K Schwamborn

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R Weil

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S T Whiteside

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P2860

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

The NF-kappa B and I kappa B proteins: new discoveries and insights

Interaction of an adenovirus E3 14.7-kilodalton protein with a novel tumor necrosis factor alpha-inducible cellular protein containing leucine zipper domains

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

I kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

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22780-9

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3921074

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10.1074/JBC.M001500200

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275

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10807909

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