Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase
about
Identification of endoglycan, a member of the CD34/podocalyxin family of sialomucinsSulfated glycosaminoglycans are required for specific and sensitive fibroblast growth factor (FGF) 19 signaling via FGF receptor 4 and betaKlothoFibroblast growth factor-2 binds to small heparin-derived oligosaccharides and stimulates a sustained phosphorylation of p42/44 mitogen-activated protein kinase and proliferation of rat mammary fibroblastsIncreased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient miceA mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic micePersonalized Clinical Trials in Hepatocellular Carcinoma Based on Biomarker SelectionStructural basis of heparan sulfate-specific degradation by heparinase IIIElevated cholesterol metabolism and bile acid synthesis in mice lacking membrane tyrosine kinase receptor FGFR4Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cellsTargeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse modelsInterferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivoThe extracellular matrix in development and morphogenesis: a dynamic view.Evidence for digenic inheritance in some cases of Antley-Bixler syndrome?Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infectionRole of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome.Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo.Not all perlecans are created equal: interactions with fibroblast growth factor (FGF) 2 and FGF receptors.Heparin and liver heparan sulfate can rescue hepatoma cells from topotecan action.Deficiency of metabolic regulator FGFR4 delays breast cancer progression through systemic and microenvironmental metabolic alterations.βKlotho suppresses tumor growth in hepatocellular carcinoma by regulating Akt/GSK-3β/cyclin D1 signaling pathway.Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathwayCo-administration of cyclosporine an alleviates thioacetamide-induced liver injury.Endovascular laser–tissue interactions and biological responses in relation to endovenous laser therapy.Activated hepatic stellate cells express keratinocyte growth factor in chronic liver diseaseFibroblast growth factor receptor isotype expression and its association with overall survival in patients with hepatocellular carcinoma.Fibroblast growth factor receptor 4 polymorphism is associated with liver cirrhosis in hepatocarcinomaMechanistic diversity of cytokine receptor signaling across cell membranes.Role of fibroblast growth factor type 1 and 2 in carbon tetrachloride-induced hepatic injury and fibrogenesis.Klotho-beta overexpression as a novel target for suppressing proliferation and fibroblast growth factor receptor-4 signaling in hepatocellular carcinoma.Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assemblyEndothelial heparan sulfate 6-O-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.Identification of FGFR4 as a potential therapeutic target for advanced-stage, high-grade serous ovarian cancerFibroblast growth factors, old kids on the new block.Differential sulfation remodelling of heparan sulfate by extracellular 6-O-sulfatases regulates fibroblast growth factor-induced boundary formation by glial cells: implications for glial cell transplantation.FGFR4 and TGF-β1 expression in hepatocellular carcinoma: correlation with clinicopathological features and prognosis.Signals and cells involved in regulating liver regeneration.Targeted inhibition of the FGF19-FGFR4 pathway in hepatocellular carcinoma; translational safety considerations.Binding of heparin/heparan sulfate to fibroblast growth factor receptor 4.Targeting fibroblast growth factor 19 in liver disease: a potential biomarker and therapeutic target.
P2860
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P2860
Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase
description
1999 nî lūn-bûn
@nan
1999 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Specificity for fibroblast gro ...... mplex with the receptor kinase
@ast
Specificity for fibroblast gro ...... mplex with the receptor kinase
@en
Specificity for fibroblast gro ...... mplex with the receptor kinase
@nl
type
label
Specificity for fibroblast gro ...... mplex with the receptor kinase
@ast
Specificity for fibroblast gro ...... mplex with the receptor kinase
@en
Specificity for fibroblast gro ...... mplex with the receptor kinase
@nl
prefLabel
Specificity for fibroblast gro ...... mplex with the receptor kinase
@ast
Specificity for fibroblast gro ...... mplex with the receptor kinase
@en
Specificity for fibroblast gro ...... mplex with the receptor kinase
@nl
P2093
P2860
P3181
P356
P1476
Specificity for fibroblast gro ...... mplex with the receptor kinase
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.274.22.15947
P407
P577
1999-05-28T00:00:00Z