SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
about
Interleukin 9 induces expression of three cytokine signal inhibitors: cytokine-inducible SH2-containing protein, suppressor of cytokine signalling (SOCS)-2 and SOCS-3, but only SOCS-3 overexpression suppresses interleukin 9 signallingRegulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1.SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardationFunctional analysis of Asb-1 using genetic modification in micePlacental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3Signaling by STATsJoint disease caused by defective gp130-mediated STAT signaling.Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation.Negative regulation of cytokine signaling and immune responses by SOCS proteinsAn alternative and effective HIV vaccination approach based on inhibition of antigen presentation attenuators in dendritic cells.Differential effects of type I and II interferons on myeloid cells and resistance to intracellular bacterial infectionsRole of suppressor of cytokine signaling-1 in murine atherosclerosisSOCS1 Mimetics and Antagonists: A Complementary Approach to Positive and Negative Regulation of Immune FunctionExpression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational controlSuppressor of cytokine signaling 1 interacts with the macrophage colony-stimulating factor receptor and negatively regulates its proliferation signalCytokine signaling in the brain: putting a SOCS in it?Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signalingSuppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanismsLethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNAThe SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivoSOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient micePim serine/threonine kinases regulate the stability of Socs-1 proteinTyrosine-phosphorylated SOCS3 interacts with the Nck and Crk-L adapter proteins and regulates Nck activation.Constitutive phosphorylation of interferon receptor A-associated signaling proteins in systemic lupus erythematosus.Negative regulation of receptor tyrosine kinase signals.Detailed analysis of gene expression during development of T cell lineages in the thymus.Lower expression of TLR2 and SOCS-3 is associated with Schistosoma haematobium infection and with lower risk for allergic reactivity in children living in a rural area in GhanaIntracellular delivery of a cell-penetrating SOCS1 that targets IFN-gamma signaling.A switch from a gradient to a threshold mode in the regulation of a transcriptional cascade promotes robust execution of meiosis in budding yeastSOCS1 and SOCS3 in the control of CNS immunityType-I IFN signaling suppresses an excessive IFN-gamma response and thus prevents lung damage and chronic inflammation during Pneumocystis (PC) clearance in CD4 T cell-competent mice.Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models.Polycystic kidneys and chronic inflammatory lesions are the delayed consequences of loss of the suppressor of cytokine signaling-1 (SOCS-1).STAT signaling in the pathogenesis and treatment of leukemias.The role of Stat5a and Stat5b in signaling by IL-2 family cytokines.Cell invasion and strain dependent induction of suppressor of cytokine signaling-1 by Toxoplasma gondiiInterferons, signal transduction pathways, and the central nervous system.Feedback control of intercellular signalling in development.New mimetic peptides of the kinase-inhibitory region (KIR) of SOCS1 through focused peptide libraries.Activation of STAT proteins and growth control.
P2860
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P2860
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
description
1999 nî lūn-bûn
@nan
1999 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@ast
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@en
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@nl
type
label
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@ast
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@en
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@nl
prefLabel
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@ast
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@en
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@nl
P2093
P3181
P1433
P1476
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
@en
P2093
A Yoshimura
D J Topham
E Parganas
J C Marine
P304
P3181
P356
10.1016/S0092-8674(00)80048-3
P407
P577
1999-09-03T00:00:00Z