M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex
about
Polo-like kinase 1 is involved in hepatitis C virus replication by hyperphosphorylating NS5AThe crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complexMaintaining Genome Stability in Defiance of Mitotic DNA DamagePLK1, A Potential Target for Cancer TherapyMolding BRCA2 function through its interacting partnersSpatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates cytokinesisA genetic screen identifies BRCA2 and PALB2 as key regulators of G2 checkpoint maintenanceHyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.BRCA2 coordinates the activities of cell-cycle kinases to promote genome stabilityThe transcription factor YY1 is a substrate for Polo-like kinase 1 at the G2/M transition of the cell cycle.Polo-box domain: a versatile mediator of polo-like kinase function.Regulatory functional territory of PLK-1 and their substrates beyond mitosis.An entire exon 3 germ-line rearrangement in the BRCA2 gene: pathogenic relevance of exon 3 deletion in breast cancer predispositionUnderstanding cytokinesis failure.Missense variants of uncertain significance (VUS) altering the phosphorylation patterns of BRCA1 and BRCA2.Identification of potential Plk1 targets in a cell-cycle specific proteome through structural dynamics of kinase and Polo box-mediated interactionsRegulators of homologous recombination repair as novel targets for cancer treatment.Structure and function of Polo-like kinases.The roles of BRCA1 and BRCA2 and associated proteins in the maintenance of genomic stability.In vitro phosphorylation of BRCA2 by the checkpoint kinase CHEK2.BRCA2 minor transcript lacking exons 4-7 supports viability in mice and may account for survival of humans with a pathogenic biallelic mutation.Novel BRCA2-interacting protein BJ-HCC-20A inhibits the induction of apoptosis in response to DNA damage.Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cellsCtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression.HDAC2/3 binding and deacetylation of BubR1 initiates spindle assembly checkpoint silencing.Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer.
P2860
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P2860
M phase-specific phosphorylation of BRCA2 by Polo-like kinase 1 correlates with the dissociation of the BRCA2-P/CAF complex
description
2003 nî lūn-bûn
@nan
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@ast
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@en
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@nl
type
label
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@ast
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@en
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@nl
prefLabel
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@ast
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@en
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@nl
P2093
P2860
P3181
P356
P1476
M phase-specific phosphorylati ...... ion of the BRCA2-P/CAF complex
@en
P2093
Horng-Ru Lin
Nicholas S Y Ting
Wen-Hwa Lee
P2860
P304
P3181
P356
10.1074/JBC.M210659200
P407
P577
2003-09-19T00:00:00Z