Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival
about
A critical re-assessment of DNA repair gene promoter methylation in non-small cell lung carcinomaEpigenetic screen of human DNA repair genes identifies aberrant promoter methylation of NEIL1 in head and neck squamous cell carcinomaEpigenetic changes of DNA repair genes in cancerSusceptibility pathways in Fanconi's anemia and breast cancerCpG methylation of the FHIT, FANCF, cyclin-D2, BRCA2 and RUNX3 genes in Granulosa cell tumors (GCTs) of ovarian originEpigenetics of cervical cancer. An overview and therapeutic perspectivesBeyond Breast and Ovarian Cancers: PARP Inhibitors for BRCA Mutation-Associated and BRCA-Like Solid TumorsComponents of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.Fancf-deficient mice are prone to develop ovarian tumoursPromoter Hypermethylation of FANCF and Susceptibility and Prognosis of Epithelial Ovarian CancerThe Fanconi anemia gene product FANCF is a flexible adaptor proteinInter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair researchGenome stability pathways in head and neck cancersThe Fanconi anemia pathway and ubiquitinHallmarks of 'BRCAness' in sporadic cancersBRCA1: a novel prognostic factor in resected non-small-cell lung cancerModeling cancer progression via pathway dependenciesThe ubiquitin system, disease, and drug discovery.Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression.Assessing the function of homologous recombination DNA repair in malignant pleural effusion (MPE) samples.Inactivation of the tumor suppressor genes causing the hereditary syndromes predisposing to head and neck cancer via promoter hypermethylation in sporadic head and neck cancersDNA methyltransferases, DNA damage repair, and cancerGene silencing of FANCF potentiates the sensitivity to mitoxantrone through activation of JNK and p38 signal pathways in breast cancer cellsNanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.RAD51C--a new human cancer susceptibility gene for sporadic squamous cell carcinoma of the head and neck (HNSCC).Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex.Biomarkers in early-stage non-small-cell lung cancer: current concepts and future directions.Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1.The Fanconi anemia pathway and ICL repair: implications for cancer therapy.Quantitative methodology is critical for assessing DNA methylation and impacts on correlation with patient outcomeSubpathway Analysis based on Signaling-Pathway Impact Analysis of Signaling PathwayFanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated.Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma.Celastrol induces proteasomal degradation of FANCD2 to sensitize lung cancer cells to DNA crosslinking agents.Fanconi anemia genes in lung adenocarcinoma- a pathway-wide study on cancer susceptibilityHawaii natural compounds are promising to reduce ovarian cancer deathsCell-based high-throughput screens for the discovery of chemotherapeutic agents.Pharmacogenomics in lung cancer: an analysis of DNA repair gene expression in patients treated with platinum-based chemotherapy.FANCA safeguards interphase and mitosis during hematopoiesis in vivo.Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer.
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P2860
Inactivation of the Fanconi anemia/BRCA pathway in lung and oral cancers: implications for treatment and survival
description
2004 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Januar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: 29 January 2004)
@en
vedecký článok (publikovaný 2004/01/29)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/01/29)
@nl
наукова стаття, опублікована в січні 2004
@uk
مقالة علمية (نشرت في 29-1-2004)
@ar
name
Inactivation of the Fanconi an ...... ons for treatment and survival
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Inactivation of the Fanconi an ...... ons for treatment and survival
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Inactivation of the Fanconi an ...... ons for treatment and survival
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type
label
Inactivation of the Fanconi an ...... ons for treatment and survival
@ast
Inactivation of the Fanconi an ...... ons for treatment and survival
@en
Inactivation of the Fanconi an ...... ons for treatment and survival
@nl
prefLabel
Inactivation of the Fanconi an ...... ons for treatment and survival
@ast
Inactivation of the Fanconi an ...... ons for treatment and survival
@en
Inactivation of the Fanconi an ...... ons for treatment and survival
@nl
P2093
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P1476
Inactivation of the Fanconi an ...... ons for treatment and survival
@en
P2093
Karl T Kelsey
Makoto Suzuki
Marshall Posner
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P2888
P304
P3181
P356
10.1038/SJ.ONC.1207256
P407
P577
2004-01-29T00:00:00Z
P5875
P6179
1033032381