Inhibitors of tick-borne flavivirus reproduction from structure-based virtual screeningSynthesis and Evaluation of Metabotropic Glutamate Receptor Subtype 5 Antagonists Based on FenobamSMARTCyp: A 2D Method for Prediction of Cytochrome P450-Mediated Drug MetabolismEnantiopure Cyclopropane-Bearing Pyridyldiazabicyclo[3.3.0]octanes as Selective α4β2-nAChR Ligands.Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein–Protein InteractionOxabicyclooctane-Linked Novel Bacterial Topoisomerase Inhibitors as Broad Spectrum Antibacterial AgentsDiscovery of a Highly Selective JAK2 Inhibitor, BMS-911543, for the Treatment of Myeloproliferative NeoplasmsDiscovery of MK-8718, an HIV Protease Inhibitor Containing a Novel Morpholine Aspartate Binding GroupDiscovery of Potent and Selective Inhibitors of CDPK1 from C. parvum and T. gondiiThermodynamic and Structural Effects of Macrocyclization as a Constraining Method in Protein-Ligand Interactions.Elucidation of New Binding Interactions with the Human Tsg101 Protein Using Modified HIV-1 Gag-p6 Derived Peptide LigandsStructures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate ComplexesSubstrate-Selective Inhibition of Cyclooxygenase-2: Development and Evaluation of Achiral Profen ProbesOptimized 5-Membered Heterocycle-Linked Pterins for the Inhibition of Ricin Toxin AStructure-Based Discovery of a Novel Pentamidine-Related Inhibitor of the Calcium-Binding Protein S100BDiscovery of an Orally Available, Brain Penetrant BACE1 Inhibitor That Affords Robust CNS Aβ ReductionMolecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Antidiabetes DrugsChemo-Immunotherapeutic Antimalarials Targeting Isoprenoid BiosynthesisStructure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic CharacterizationAntimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate ReductoisomeraseCrystallographic Investigation and Selective Inhibition of Mutant Isocitrate DehydrogenaseDiscovery of Protein–Protein Interaction Inhibitors of Replication Protein ASAR-Based Optimization of a 4-Quinoline Carboxylic Acid Analogue with Potent Antiviral ActivityDiscovery of Small Molecule Mer Kinase Inhibitors for the Treatment of Pediatric Acute Lymphoblastic LeukemiaHIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid BiosynthesisIs NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein–Protein Interactions?Discovery of Potent and Selective Inhibitors of Toxoplasma gondii Thymidylate Synthase for Opportunistic InfectionsPotent and Selective Inhibitors of CDPK1 from T. gondii and C. parvum Based on a 5-Aminopyrazole-4-carboxamide ScaffoldAccessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase InhibitorsDiscovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of RapamycinCarbamylation of N-Terminal ProlineDiscovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical UtilityInhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum ProliferationStructure Guided Development of Potent Reversibly Binding Penicillin Binding Protein InhibitorsPyrazolopyridine Inhibitors of B-Raf V600E . Part 1: The Development of Selective, Orally Bioavailable, and Efficacious InhibitorsDiscovery of S -Nitrosoglutathione Reductase Inhibitors: Potential Agents for the Treatment of Asthma and Other Inflammatory DiseasesInhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding SiteDiscovery of a Novel Chemotype of Tyrosine Kinase Inhibitors by Fragment-Based Docking and Molecular DynamicsA Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase
P1433
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P1433
description
begutachtete wissenschaftliche Fachzeitschrift
@de
peer-reviewed scientific journal
@en
revista científica
@es
rivista scientifica
@it
vědecký časopis
@cs
wetenschappelijk tijdschrift van American Chemical Society
@nl
рецензований науковий журнал
@uk
वैज्ञानिक पत्रिका
@hi
英语期刊
@zh
name
A C S Medicinal Chemistry Letters
@da
ACS Medicinal Chemistry Letters
@ast
ACS Medicinal Chemistry Letters
@de
ACS Medicinal Chemistry Letters
@en
ACS Medicinal Chemistry Letters
@es
ACS Medicinal Chemistry Letters
@fi
ACS Medicinal Chemistry Letters
@fr
ACS Medicinal Chemistry Letters
@it
ACS Medicinal Chemistry Letters
@nb
ACS Medicinal Chemistry Letters
@nl
type
label
A C S Medicinal Chemistry Letters
@da
ACS Medicinal Chemistry Letters
@ast
ACS Medicinal Chemistry Letters
@de
ACS Medicinal Chemistry Letters
@en
ACS Medicinal Chemistry Letters
@es
ACS Medicinal Chemistry Letters
@fi
ACS Medicinal Chemistry Letters
@fr
ACS Medicinal Chemistry Letters
@it
ACS Medicinal Chemistry Letters
@nb
ACS Medicinal Chemistry Letters
@nl
prefLabel
A C S Medicinal Chemistry Letters
@da
ACS Medicinal Chemistry Letters
@ast
ACS Medicinal Chemistry Letters
@de
ACS Medicinal Chemistry Letters
@en
ACS Medicinal Chemistry Letters
@es
ACS Medicinal Chemistry Letters
@fi
ACS Medicinal Chemistry Letters
@fr
ACS Medicinal Chemistry Letters
@it
ACS Medicinal Chemistry Letters
@nb
ACS Medicinal Chemistry Letters
@nl
P3181
P4616
P1055
P1058
P1156
19700177127
P1159
P1250
P1277
P1476
ACS Medicinal Chemistry Letters
@en
P236
P3181
P407
P571
2010-01-01T00:00:00Z