The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels
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Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordatesAnalysis of the interactions between the C-terminal cytoplasmic domains of KCNQ1 and KCNE1 channel subunitsInhibition of human ether à go-go potassium channels by Ca2+/calmodulin binding to the cytosolic N- and C-terminiThe KCNQ1 (Kv7.1) COOH terminus, a multitiered scaffold for subunit assembly and protein interactionIntracellular domains interactions and gated motions of I(KS) potassium channel subunitsComparison of K+-channel genes within the genomes of Anopheles gambiae and Drosophila melanogasterDriving with no brakes: molecular pathophysiology of Kv7 potassium channelsStructure of a Ca2+/CaM:Kv7.4 (KCNQ4) B-Helix Complex Provides Insight into M Current ModulationCharacterization of calmodulin binding to the orphan nuclear receptor ErrgammaComplete loss of the cytoplasmic carboxyl terminus of the KCNQ2 potassium channel: a novel mutation in a large Czech pedigree with benign neonatal convulsions or other epileptic phenotypesMolecular determinants of Ca(2+)/calmodulin-dependent regulation of Ca(v)2.1 channelsNeurotransmitter modulation of small-conductance Ca2+-activated K+ channels by regulation of Ca2+ gatingCoordinated signal integration at the M-type potassium channel upon muscarinic stimulationCa2+/calmodulin disrupts AKAP79/150 interactions with KCNQ (M-Type) K+ channelsDeterminants within the turret and pore-loop domains of KCNQ3 K+ channels governing functional activity.Selective interaction of syntaxin 1A with KCNQ2: possible implications for specific modulation of presynaptic activity.Calmodulin interaction with hEAG1 visualized by FRET microscopyChannel-anchored protein kinase CK2 and protein phosphatase 1 reciprocally regulate KCNQ2-containing M-channels via phosphorylation of calmodulin.Calmodulation meta-analysis: predicting calmodulin binding via canonical motif clustering.Structural requirements for differential sensitivity of KCNQ K+ channels to modulation by Ca2+/calmodulin.Polarized axonal surface expression of neuronal KCNQ potassium channels is regulated by calmodulin interaction with KCNQ2 subunit.Kv7 channels can function without constitutive calmodulin tetheringExpression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability.Identification by mass spectrometry and functional characterization of two phosphorylation sites of KCNQ2/KCNQ3 channels.Ginseng gintonin activates the human cardiac delayed rectifier K+ channel: involvement of Ca2+/calmodulin binding sites.Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linkerA change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activityCalcium and arrhythmogenesis.The therapeutic potential of neuronal KCNQ channel modulators.Coupling of voltage-sensors to the channel pore: a comparative viewStructural insights into neuronal K+ channel-calmodulin complexes.Phosphatidylinositol-4,5-bisphosphate, PIP2, controls KCNQ1/KCNE1 voltage-gated potassium channels: a functional homology between voltage-gated and inward rectifier K+ channels.Calmodulin mediates Ca2+-dependent modulation of M-type K+ channelsMechanisms of Calmodulin Regulation of Different Isoforms of Kv7.4 K+ ChannelsCalmodulin and CaMKII as molecular switches for cardiac ion channels.Channelopathies in idiopathic epilepsy.A carboxy-terminal inter-helix linker as the site of phosphatidylinositol 4,5-bisphosphate action on Kv7 (M-type) K+ channels.Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity.The C-terminus of Kv7 channels: a multifunctional module.Calmodulin activation limits the rate of KCNQ2 K+ channel exit from the endoplasmic reticulum.
P2860
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P2860
The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels
description
2002 nî lūn-bûn
@nan
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The identification and charact ...... endent KCNQ potassium channels
@ast
The identification and charact ...... endent KCNQ potassium channels
@en
The identification and charact ...... endent KCNQ potassium channels
@nl
type
label
The identification and charact ...... endent KCNQ potassium channels
@ast
The identification and charact ...... endent KCNQ potassium channels
@en
The identification and charact ...... endent KCNQ potassium channels
@nl
prefLabel
The identification and charact ...... endent KCNQ potassium channels
@ast
The identification and charact ...... endent KCNQ potassium channels
@en
The identification and charact ...... endent KCNQ potassium channels
@nl
P2093
P356
P1476
The identification and charact ...... endent KCNQ potassium channels
@en
P2093
Alvaro Villarroel
Eva Yus-Najera
Irene Santana-Castro
P304
P356
10.1074/JBC.M204130200
P407
P577
2002-08-09T00:00:00Z