The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila
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Domains of human U4atac snRNA required for U12-dependent splicing in vivoU7 snRNA mutations in Drosophila block histone pre-mRNA processing and disrupt oogenesisTargeted 'knockdown' of spliceosome function in mammalian cellsMutations in U4atac snRNA, a component of the minor spliceosome, in the developmental disorder MOPD IAn intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomesIdentification of an evolutionarily divergent U11 small nuclear ribonucleoprotein particle in DrosophilaAn early evolutionary origin for the minor spliceosomeThe significant other: splicing by the minor spliceosomeAssociation of TALS developmental disorder with defect in minor splicing component U4atac snRNASurprisingly high number of Twintrons in vertebratesThe minor spliceosomal protein U11/U12-31K is an RNA chaperone crucial for U12 intron splicing and the development of dicot and monocot plants.Gene expression profiling of U12-type spliceosome mutant Drosophila reveals widespread changes in metabolic pathwaysGlobal analysis of the nuclear processing of transcripts with unspliced U12-type introns by the exosome.The U11/U12 snRNP 65K protein acts as a molecular bridge, binding the U12 snRNA and U11-59K proteinThe splicing of U12-type introns can be a rate-limiting step in gene expression.Branchpoint selection in the splicing of U12-dependent introns in vitroComprehensive splice-site analysis using comparative genomics.Aberrant splicing of U12-type introns is the hallmark of ZRSR2 mutant myelodysplastic syndrome.Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal developmentBRR2a Affects Flowering Time via FLC SplicingA Drosophila model of spinal muscular atrophy uncouples snRNP biogenesis functions of survival motor neuron from locomotion and viability defects.Free energy landscapes of RNA/RNA complexes: with applications to snRNA complexes in spliceosomes.Convergent evolution of twintron-like configurations: One is never enough.The Arabidopsis homolog of human minor spliceosomal protein U11-48K plays a crucial role in U12 intron splicing and plant developmentDrosophila hnRNP A1 homologs Hrp36/Hrp38 enhance U2-type versus U12-type splicing to regulate alternative splicing of the prospero twintron.Minor intron splicing is regulated by FUS and affected by ALS-associated FUS mutantsAberrant splicing in maize rough endosperm3 reveals a conserved role for U12 splicing in eukaryotic multicellular development.Evolutionarily conserved exon definition interactions with U11 snRNP mediate alternative splicing regulation on U11-48K and U11/U12-65K genes.Minor splicing snRNAs are enriched in the developing mouse CNS and are crucial for survival of differentiating retinal neurons.An SMN-dependent U12 splicing event essential for motor circuit functionThe Arabidopsis U12-type spliceosomal protein U11/U12-31K is involved in U12 intron splicing via RNA chaperone activity and affects plant development.Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA.RNA-RNA interaction prediction based on multiple sequence alignments.quatre-quart1 is an indispensable U12 intron-containing gene that plays a crucial role in Arabidopsis development.The Arabidopsis U11/U12-65K is an indispensible component of minor spliceosome and plays a crucial role in U12 intron splicing and plant development.
P2860
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P2860
The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila
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2002 nî lūn-bûn
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2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The divergent U12-type spliceo ...... for development in Drosophila
@ast
The divergent U12-type spliceo ...... for development in Drosophila
@en
The divergent U12-type spliceo ...... for development in Drosophila
@nl
type
label
The divergent U12-type spliceo ...... for development in Drosophila
@ast
The divergent U12-type spliceo ...... for development in Drosophila
@en
The divergent U12-type spliceo ...... for development in Drosophila
@nl
prefLabel
The divergent U12-type spliceo ...... for development in Drosophila
@ast
The divergent U12-type spliceo ...... for development in Drosophila
@en
The divergent U12-type spliceo ...... for development in Drosophila
@nl
P2093
P3181
P1433
P1476
The divergent U12-type spliceo ...... for development in Drosophila
@en
P2093
Carl Hashimoto
Leo R Otake
Petra Scamborova
P304
P3181
P356
10.1016/S1097-2765(02)00441-0
P407
P577
2002-02-01T00:00:00Z