Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin
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A novel role of RASSF9 in maintaining epidermal homeostasisYap1 acts downstream of α-catenin to control epidermal proliferationContact inhibition of VEGF-induced proliferation requires vascular endothelial cadherin, beta-catenin, and the phosphatase DEP-1/CD148Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activationLinks between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skinAlpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly.Re-solving the cadherin-catenin-actin conundrumα-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1p120-catenin mediates inflammatory responses in the skinScratching the surface of skin developmentEpidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasisp14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasisAP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermisThe E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression.Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis.Cadherin signaling: keeping cells in touchProtein N-glycosylation in oral cancer: dysregulated cellular networks among DPAGT1, E-cadherin adhesion and canonical Wnt signalingRegulation of classical cadherin membrane expression and F-actin assembly by alpha-catenins, during Xenopus embryogenesisαE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth developmentDimer asymmetry defines α-catenin interactionsDLC1 interaction with α-catenin stabilizes adherens junctions and enhances DLC1 antioncogenic activityNew functions for alpha-catenins in health and disease: from cancer to heart regenerationBRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progenyProtein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytesMammalian formin-1 participates in adherens junctions and polymerization of linear actin cablesA role for the primary cilium in Notch signaling and epidermal differentiation during skin developmentNF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctionsAlpha-catenin is essential in intestinal adenoma formationalphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathwayLoss of cell polarity causes severe brain dysplasia in Lgl1 knockout miceTranscriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cellsCdc42 controls progenitor cell differentiation and beta-catenin turnover in skinLis1 is essential for cortical microtubule organization and desmosome stability in the epidermisE-cadherin is essential for in vivo epidermal barrier function by regulating tight junctionsGoverning epidermal homeostasis by coupling cell-cell adhesion to integrin and growth factor signaling, proliferation, and apoptosisAsymmetric cell divisions promote stratification and differentiation of mammalian skin.PDZ domain proteins: plug and play!Junctional music that the nucleus hears: cell-cell contact signaling and the modulation of gene activity.The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes.
P2860
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P2860
Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@ast
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@en
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@nl
type
label
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@ast
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@en
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@nl
prefLabel
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@ast
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@en
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@nl
P2093
P3181
P1433
P1476
Hyperproliferation and defects ...... ation of alpha-catenin in skin
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(01)00246-X
P407
P50
P577
2001-02-01T00:00:00Z