A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor
about
PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunitSTAT3 and MITF cooperatively induce cellular transformation through upregulation of c-fos expressionNonconventional involvement of LysRS in the molecular mechanism of USF2 transcriptional activity in FcepsilonRI-activated mast cellsDevelopment, migration, and survival of mast cellsActivation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)Importin beta plays an essential role in the regulation of the LysRS-Ap(4)A pathway in immunologically activated mast cellsDiadenosine tetraphosphate hydrolase is part of the transcriptional regulation network in immunologically activated mast cellsTranscription factor MITF regulates cardiac growth and hypertrophySignaling Pathways in MelanogenesisSumoylation of MITF and its related family members TFE3 and TFEBThe 'PINIT' motif, of a newly identified conserved domain of the PIAS protein family, is essential for nuclear retention of PIAS3LPIAS3 induces SUMO-1 modification and transcriptional repression of IRF-1Regulation of gene-activation pathways by PIAS proteins in the immune systemMelanoma inhibitory activity (MIA): an important molecule in melanoma development and progression.Role played by microphthalmia transcription factor phosphorylation and its Zip domain in its transcriptional inhibition by PIAS3Towards a quantitative understanding of the MITF-PIAS3-STAT3 connectionSumoylation modulates transcriptional activity of MITF in a promoter-specific mannerThe transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.Loss of CITED1, an MITF regulator, drives a phenotype switch in vitro and can predict clinical outcome in primary melanoma tumours.Identification of STAT3-independent regulatory effects for protein inhibitor of activated STAT3 by binding to novel transcription factors.The transcription network regulating melanocyte development and melanoma.PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts.The role played by key transcription factors in activated mast cells.Cytokine signaling in the differentiation of innate effector cellsProtein Inhibitor of Activated STAT3 (PIAS3) Is Down-Regulated in Eutopic Endometrium of Women with Endometriosis.Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice.The microphthalmia-associated transcription factor Mitf interacts with beta-catenin to determine target gene expressionMicrophthalmia transcription factor isoforms in mast cells and the heart.Interplay between MITF, PIAS3, and STAT3 in mast cells and melanocytes.Nuclear Smad6 promotes gliomagenesis by negatively regulating PIAS3-mediated STAT3 inhibition.
P2860
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P2860
A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor
description
2001 nî lūn-bûn
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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
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2001年論文
@zh-hant
2001年論文
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2001年論文
@zh-mo
2001年論文
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2001年论文
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name
A new role for the STAT3 inhib ...... phthalmia transcription factor
@ast
A new role for the STAT3 inhib ...... phthalmia transcription factor
@en
A new role for the STAT3 inhib ...... phthalmia transcription factor
@nl
type
label
A new role for the STAT3 inhib ...... phthalmia transcription factor
@ast
A new role for the STAT3 inhib ...... phthalmia transcription factor
@en
A new role for the STAT3 inhib ...... phthalmia transcription factor
@nl
altLabel
A New Role for the STAT3 Inhibitor, PIAS3
@en
prefLabel
A new role for the STAT3 inhib ...... phthalmia transcription factor
@ast
A new role for the STAT3 inhib ...... phthalmia transcription factor
@en
A new role for the STAT3 inhib ...... phthalmia transcription factor
@nl
P2093
P2860
P3181
P356
P1476
A New Role for the STAT3 Inhibitor, PIAS3
@en
A new role for the STAT3 inhib ...... phthalmia transcription factor
@en
P2093
Carmit Levy
Ehud Razin
Hovav Nechushtan
P2860
P3181
P356
10.1074/JBC.M109236200
P407
P577
2001-11-14T00:00:00Z
2002-01-18T00:00:00Z