Two overlapping reading frames in a single exon encode interacting proteins--a novel way of gene usage
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Direct detection of alternative open reading frames translation products in human significantly expands the proteomeOverlapping of MINK and CHRNE gene loci in the course of mammalian evolutionRapid asymmetric evolution of a dual-coding tumor suppressor INK4a/ARF locus contradicts its functionOscillating evolution of a mammalian locus with overlapping reading frames: an XLalphas/ALEX relay.Statistical evidence for conserved, local secondary structure in the coding regions of eukaryotic mRNAs and pre-mRNAs.Multiple sequence alignments of partially coding nucleic acid sequences.To Know How a Gene Works, We Need to Redefine It First but then, More Importantly, to Let the Cell Itself Decide How to Transcribe and Process Its RNAsGene Dosage Effects at the Imprinted Gnas ClusterGene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASKXLalphas, the extra-long form of the alpha-subunit of the Gs G protein, is significantly longer than suspected, and so is its companion AlexDifferential expression and antibacterial activity of epididymis protein 2 isoforms in the male reproductive tract of human and rhesus monkey (Macaca mulatta)MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA.A first look at ARFome: dual-coding genes in mammalian genomesBioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts.Dual coding in alternative reading frames correlates with intrinsic protein disorder.Exploring the selective constraint on the sizes of insertions and deletions in 5' untranslated regions in mammalsDeletion of the noncoding GNAS antisense transcript causes pseudohypoparathyroidism type Ib and biparental defects of GNAS methylation in cisAn out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting proteinThe role of GNAS and other imprinted genes in the development of obesity.Postnatal changes in the expression pattern of the imprinted signalling protein XLαs underlie the changing phenotype of deficient mice.Detection of functional overlapping genes: simulation and case studies.Phylogenetic patterns of emergence of new genes support a model of frequent de novo evolution.Locating protein-coding sequences under selection for additional, overlapping functions in 29 mammalian genomes.New mutations at the imprinted Gnas cluster show gene dosage effects of Gsα in postnatal growth and implicate XLαs in bone and fat metabolism but not in suckling.Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells.Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology.The G protein α subunit variant XLαs promotes inositol 1,4,5-trisphosphate signaling and mediates the renal actions of parathyroid hormone in vivo.Death of a dogma: eukaryotic mRNAs can code for more than one protein.GeneTack database: genes with frameshifts in prokaryotic genomes and eukaryotic mRNA sequencesLessons learned from the initial sequencing of the pig genome: comparative analysis of an 8 Mb region of pig chromosome 17.The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted TranscriptsThe A2A adenosine receptor is a dual coding gene: a novel mechanism of gene usage and signal transduction.Small proteins encoded by unannotated ORFs are rising stars of the proteome, confirming shortcomings in genome annotations and current vision of an mRNA.Length of the ORF, position of the first AUG and the Kozak motif are important factors in potential dual-coding transcripts.HAltORF: a database of predicted out-of-frame alternative open reading frames in human.Extensively overlapping reading frames in a second mammalian gene.The imprinted signaling protein XL alpha s is required for postnatal adaptation to feeding.A missense mutation in the non-neural G-protein alpha-subunit isoforms modulates susceptibility to obesity.Mitochondrial dual-coding genes in Trypanosoma brucei.
P2860
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P2860
Two overlapping reading frames in a single exon encode interacting proteins--a novel way of gene usage
description
2001 nî lūn-bûn
@nan
2001 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Two overlapping reading frames ...... ins--a novel way of gene usage
@ast
Two overlapping reading frames ...... ins--a novel way of gene usage
@en
Two overlapping reading frames ...... ins--a novel way of gene usage
@nl
type
label
Two overlapping reading frames ...... ins--a novel way of gene usage
@ast
Two overlapping reading frames ...... ins--a novel way of gene usage
@en
Two overlapping reading frames ...... ins--a novel way of gene usage
@nl
prefLabel
Two overlapping reading frames ...... ins--a novel way of gene usage
@ast
Two overlapping reading frames ...... ins--a novel way of gene usage
@en
Two overlapping reading frames ...... ins--a novel way of gene usage
@nl
P2860
P3181
P356
P1433
P1476
Two overlapping reading frames ...... ins--a novel way of gene usage
@en
P2093
P2860
P304
P3181
P356
10.1093/EMBOJ/20.14.3849
P407
P577
2001-07-01T00:00:00Z