The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis
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The transcription factor p53: not a repressor, solely an activatorFhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cellsCommunity structure analysis of transcriptional networks reveals distinct molecular pathways for early- and late-onset temporal lobe epilepsy with childhood febrile seizuresAntioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cellsThe p53-induced gene-6 (proline oxidase) mediates apoptosis through a calcineurin-dependent pathwayAdrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive oxygen species in mitochondriaOxidative Stress and Response to Thymidylate Synthase-Targeted AntimetabolitesEvidence that p53-mediated cell-cycle-arrest inhibits chemotherapeutic treatment of ovarian carcinomas.TAF6delta controls apoptosis and gene expression in the absence of p53.TAF6delta orchestrates an apoptotic transcriptome profile and interacts functionally with p53.p53 and mitochondrial function in neurons.Proteomic analysis of nuclei isolated from cancer cell lines treated with indenoisoquinoline NSC 724998, a novel topoisomerase I inhibitor.Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes.DNA polymerase eta, the product of the xeroderma pigmentosum variant gene and a target of p53, modulates the DNA damage checkpoint and p53 activation.The Regulation of Aging and Longevity: A New and Complex Role of p53.The p73 tumor suppressor is targeted by Pirh2 RING finger E3 ubiquitin ligase for the proteasome-dependent degradation.High-Resolution 4C Reveals Rapid p53-Dependent Chromatin Reorganization of the CDKN1A Locus in Response to Stress.Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.Influence of 5-fluorouracil on ferredoxin reductase mRNA splice variants in colorectal carcinomasp53-dependent stimulation of redox-related genes in the lymphoid organs of gamma-irradiated--mice identification of Haeme-oxygenase 1 as a direct p53 target geneThe critical role of catalase in prooxidant and antioxidant function of p53.Regional localisation of p53-independent apoptosis determines toxicity to 5-fluorouracil and pyrrolidinedithiocarbamate in the murine gut.The regulation of cellular metabolism by tumor suppressor p53.Vitamin D3 upregulated protein 1 (VDUP1) is a regulator for redox signaling and stress-mediated diseases.A gene signature-based approach identifies mTOR as a regulator of p73.Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functionsHomeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense.The proline-rich domain in p63 is necessary for the transcriptional and apoptosis-inducing activities of TAp63Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells.Coordinate loss of fragile gene expression in pancreatobiliary cancers: correlations among markers and clinical featuresMetabolic regulation by p53 family members.Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family.Differential recognition of response elements determines target gene specificity for p53 and p63Brucella melitensis triggers time-dependent modulation of apoptosis and down-regulation of mitochondrion-associated gene expression in mouse macrophages.ΔNp63 targets cytoglobin to inhibit oxidative stress-induced apoptosis in keratinocytes and lung cancer.A distinct p53 target gene set predicts for response to the selective p53-HDM2 inhibitor NVP-CGM097.The Paradox of p53: What, How, and Why?Census and evaluation of p53 target genes.New p63 targets in keratinocytes identified by a genome-wide approach.Olaquindox-induced apoptosis is suppressed through p38 MAPK and ROS-mediated JNK pathways in HepG2 cells.
P2860
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P2860
The ferredoxin reductase gene is regulated by the p53 family and sensitizes cells to oxidative stress-induced apoptosis
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@ast
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@en
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@nl
type
label
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@ast
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@en
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@nl
prefLabel
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@ast
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@en
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@nl
P2860
P3181
P356
P1433
P1476
The ferredoxin reductase gene ...... ative stress-induced apoptosis
@en
P2093
Xinbin Chen
P2860
P2888
P304
P3181
P356
10.1038/SJ.ONC.1205862
P407
P50
P577
2002-10-01T00:00:00Z
P5875
P6179
1028328151