p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
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Implication of checkpoint kinase-dependent up-regulation of ribonucleotide reductase R2 in DNA damage responseATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage2.6 Å X-ray Crystal Structure of Human p53R2, a p53-Inducible Ribonucleotide Reductase,Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.Subcellular localization of yeast ribonucleotide reductase regulated by the DNA replication and damage checkpoint pathwaysPhase II trial of the ribonucleotide reductase inhibitor 3-aminopyridine-2-carboxaldehydethiosemicarbazone plus gemcitabine in patients with advanced biliary tract cancerGene expression profiling defined pathways correlated with fibroblast cell proliferation induced by Opisthorchis viverrini excretory/secretory product.Mechanism of inactivation of human ribonucleotide reductase with p53R2 by gemcitabine 5'-diphosphateRegulation and functional contribution of thymidine kinase 1 in repair of DNA damagep53R2 inhibits the proliferation of human cancer cells in association with cell-cycle arrest.Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasisRibonucleotide reductase inhibitors: a new look at an old target for radiosensitization.Therapeutic doses of irradiation activate viral transcription and induce apoptosis in HIV-1 infected cells.MEK2 regulates ribonucleotide reductase activity through functional interaction with ribonucleotide reductase small subunit p53R2.PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.The critical role of catalase in prooxidant and antioxidant function of p53.Potential of Radiation-Induced Cellular Stress for Reactivation of Latent HIV-1 and Killing of Infected CellsThe predictive value of p53, p53R2, and p21 for the effect of chemoradiation therapy on oesophageal squamous cell carcinoma.Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage.Clofarabine Has Apoptotic Effect on T47D Breast Cancer Cell Line via P53R2 Gene Expressionp53-inducible ribonucleotide reductase (p53R2/RRM2B) is a DNA hypomethylation-independent decitabine gene target that correlates with clinical response in myelodysplastic syndrome/acute myelogenous leukemia.Overexpression of p53R2 is associated with poor prognosis in lung sarcomatoid carcinoma.p53R2 as a novel prognostic biomarker in nasopharyngeal carcinoma.p53R2 overexpression in cervical cancer promotes AKT signaling and EMT, and is correlated with tumor progression, metastasis and poor prognosis.[Ribonucleotide reductase and non-small cell lung cancer].
P2860
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P2860
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@ast
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@en
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@nl
type
label
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@ast
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@en
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@nl
prefLabel
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@ast
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@en
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@nl
P2093
P1433
P1476
p53R2-dependent pathway for DNA synthesis in a p53-regulated cell cycle checkpoint
@en
P2093
P304
P407
P577
2001-11-15T00:00:00Z