Hedgehog signaling in animal development: paradigms and principles
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The CK1 Family: Contribution to Cellular Stress Response and Its Role in CarcinogenesisNVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivoGli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and functionThe FU gene and its possible protein isoformsRobust network topologies for generating switch-like cellular responsesActivation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activationImmunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract developmentEvidence for the direct involvement of {beta}TrCP in Gli3 protein processingIndian hedgehog mutations causing brachydactyly type A1 impair Hedgehog signal transduction at multiple levelsMediator modulates Gli3-dependent Sonic hedgehog signalingThe crosstalk of mTOR/S6K1 and Hedgehog pathwaysThe structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signalingStructural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIPA potential role of alternative splicing in the regulation of the transcriptional activity of human GLI2 in gonadal tissues.The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1Dual function of UNC-51-like kinase 3 (Ulk3) in the Sonic hedgehog signaling pathwayStructural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/CiMice deficient in the fused homolog do not exhibit phenotypes indicative of perturbed hedgehog signaling during embryonic developmentHomozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips.Gli proteins and the control of spinal-cord patterningThe function and expansion of the Patched- and Hedgehog-related homologs in C. elegansSmall molecule modulation of Smoothened activityA genetic screen in Drosophila for identifying novel components of the hedgehog signaling pathway.The Evf-2 noncoding RNA is transcribed from the Dlx-5/6 ultraconserved region and functions as a Dlx-2 transcriptional coactivatorA gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tubeSuppressor of fused regulates Gli activity through a dual binding mechanismThe role of nutraceuticals in the regulation of Wnt and Hedgehog signaling in cancerIndian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermisGSK-3: tricks of the trade for a multi-tasking kinaseArsenic antagonizes the Hedgehog pathway by preventing ciliary accumulation and reducing stability of the Gli2 transcriptional effectorSonic hedgehog in temporal control of somite formationThe Hedgehog gene family of the cnidarian, Nematostella vectensis, and implications for understanding metazoan Hedgehog pathway evolutionA small molecule that binds Hedgehog and blocks its signaling in human cellsHeparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formationGLI2-specific transcriptional activation of the bone morphogenetic protein/activin antagonist follistatin in human epidermal cellsEstablishing and interpreting graded Sonic Hedgehog signaling during vertebrate neural tube patterning: the role of negative feedbackHedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2The magnitude of hedgehog signaling activity defines skin tumor phenotypeGli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activationDorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
P2860
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P2860
Hedgehog signaling in animal development: paradigms and principles
description
2001 nî lūn-bûn
@nan
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Hedgehog signaling in animal development: paradigms and principles
@ast
Hedgehog signaling in animal development: paradigms and principles
@en
Hedgehog signaling in animal development: paradigms and principles
@nl
type
label
Hedgehog signaling in animal development: paradigms and principles
@ast
Hedgehog signaling in animal development: paradigms and principles
@en
Hedgehog signaling in animal development: paradigms and principles
@nl
prefLabel
Hedgehog signaling in animal development: paradigms and principles
@ast
Hedgehog signaling in animal development: paradigms and principles
@en
Hedgehog signaling in animal development: paradigms and principles
@nl
P3181
P356
P1433
P1476
Hedgehog signaling in animal development: paradigms and principles
@en
P2093
A P McMahon
P W Ingham
P304
P3181
P356
10.1101/GAD.938601
P407
P577
2001-12-01T00:00:00Z