The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses
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Elongation factor-2 phosphorylation in dendrites and the regulation of dendritic mRNA translation in neuronsProtein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptideMammalian Smaug is a translational repressor that forms cytoplasmic foci similar to stress granulesThe composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAsRibosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibitionVisualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAsEnod40, a short open reading frame-containing mRNA, induces cytoplasmic localization of a nuclear RNA binding protein in Medicago truncatulaFragile X syndrome: loss of local mRNA regulation alters synaptic development and functionFMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autismRegulatory long non-coding RNAs and neuronal disordersA direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.Dendritic BC1 RNA in translational control mechanismsThe Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic ParaplegiasAdvances in the characterization of RNA-binding proteinsPRINS, a primate-specific long non-coding RNA, plays a role in the keratinocyte stress response and psoriasis pathogenesisIn Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric DisordersDysregulation and restoration of translational homeostasis in fragile X syndromeThe function of RNA-binding proteins at the synapse: implications for neurodegenerationRemote control of gene function by local translationDendritic spine dysgenesis in autism related disordersPost-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brainThe FMRP regulon: from targets to disease convergenceFrom Learning to Memory: What Flies Can Tell Us about Intellectual Disability TreatmentChannelopathies and dendritic dysfunction in fragile X syndrome.Consolidation and translation regulationRegulatory BC1 RNA and the fragile X mental retardation protein: convergent functionality in brainTherapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and BackThe Intense World Theory – A Unifying Theory of the Neurobiology of AutismKissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stabilityIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinThe G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancerBiochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathwayFrom mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndromeTDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factorGenetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Localization of FMRP-associated mRNA granules and requirement of microtubules for activity-dependent trafficking in hippocampal neuronsNormal huntingtin function: an alternative approach to Huntington's diseaseIncreased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarkerPten regulates neuronal arborization and social interaction in mice.
P2860
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P2860
The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The fragile X syndrome protein ...... of specific mRNAs at synapses
@ast
The fragile X syndrome protein ...... of specific mRNAs at synapses
@en
The fragile X syndrome protein ...... of specific mRNAs at synapses
@nl
type
label
The fragile X syndrome protein ...... of specific mRNAs at synapses
@ast
The fragile X syndrome protein ...... of specific mRNAs at synapses
@en
The fragile X syndrome protein ...... of specific mRNAs at synapses
@nl
prefLabel
The fragile X syndrome protein ...... of specific mRNAs at synapses
@ast
The fragile X syndrome protein ...... of specific mRNAs at synapses
@en
The fragile X syndrome protein ...... of specific mRNAs at synapses
@nl
P2093
P3181
P1433
P1476
The fragile X syndrome protein ...... of specific mRNAs at synapses
@en
P2093
Alessandra Di Penta
Annamaria Moro
Beatrice Primerano
Ben Oostra
Claudia Bagni
Francesca Zalfa
Marcello Giorgi
Surya Reis
P304
P3181
P356
10.1016/S0092-8674(03)00079-5
P407
P577
2003-02-07T00:00:00Z