Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
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The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin beta 4 subunit bind to ERBIN. Molecular cloning of multiple alternative splice variants of ERBIN and analysis of their tissue expressionCloning of the human type XVII collagen gene (COL17A1), and detection of novel mutations in generalized atrophic benign epidermolysis bullosaNeutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoidThe N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosomeCompound heterozygosity for a dominant glycine substitution and a recessive internal duplication mutation in the type XVII collagen gene results in junctional epidermolysis bullosa and abnormal dentitionThree novel homozygous point mutations and a new polymorphism in the COL17A1 gene: relation to biological and clinical phenotypes of junctional epidermolysis bullosaHemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180The localization of bullous pemphigoid antigen 180 (BP180) in hemidesmosomes is mediated by its cytoplasmic domain and seems to be regulated by the beta4 integrin subunit180-kD bullous pemphigoid antigen/type XVII collagen: tissue-specific expression and molecular interactions with keratin 18Shedding of collagen XVII ectodomain depends on plasma membrane microenvironmentDemonstration of the molecular shape of BP180, a 180-kDa bullous pemphigoid antigen and its potential for trimer formationTwo forms of collagen XVII in keratinocytes. A full-length transmembrane protein and a soluble ectodomainCollagen XVII is destabilized by a glycine substitution mutation in the cell adhesion domain Col15Anti-laminin gamma-1 pemphigoidShedding of Collagen XVII/BP180: STRUCTURAL MOTIFS INFLUENCE CLEAVAGE FROM CELL SURFACEProperties of the Collagen Type XVII Ectodomain: EVIDENCE FOR N- TO C-TERMINAL TRIPLE HELIX FOLDINGBullous pemphigoid sera react specifically with various domains of BP230, most frequently with C-terminal domain, by immunoblot analyses using bacterial recombinant proteins covering the entire molecule.Identification of six polymorphisms as novel susceptibility loci for ischemic or hemorrhagic stroke by exome-wide association studies.Synergy between a plasminogen cascade and MMP-9 in autoimmune diseaseRobust memory responses against influenza vaccination in pemphigus patients previously treated with rituximabAdhesion receptors in health and disease.A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180.92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.The flavonoid luteolin inhibits Fcγ-dependent respiratory burst in granulocytes, but not skin blistering in a new model of pemphigoid in adult mice.The role of complement in experimental bullous pemphigoid.Erythrodermic bullous pemphigoid.Expression of type XXIII collagen mRNA and protein.Experimental models for the autoimmune and inflammatory blistering disease, Bullous pemphigoid.New laboratory techniques for the assessment of acquired immunobullous disorders.The C5a receptor on mast cells is critical for the autoimmune skin-blistering disease bullous pemphigoid.Pemphigoid gestationis: new insights into the pathogenesis lead to novel diagnostic tools.Molecular identification of collagen 17a1 as a major genetic modifier of laminin gamma 2 mutation-induced junctional epidermolysis bullosa in mice.Keratinocytes from patients lacking collagen XVII display a migratory phenotypeTreatment of bullous pemphigoid.Dynamic interactions of epidermal collagen XVII with the extracellular matrix: laminin 332 as a major binding partnerDual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid180-kD bullous pemphigoid antigen (BP180) is deficient in generalized atrophic benign epidermolysis bullosa.The NC16A domain of collagen XVII plays a role in triple helix assembly and stabilityThe shed ectodomain of collagen XVII/BP180 is targeted by autoantibodies in different blistering skin diseases.Usefulness of Enzyme-linked Immunosorbent Assay Using Recombinant BP180 and BP230 for Serodiagnosis and Monitoring Disease Activity of Bullous Pemphigoid
P2860
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P2860
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
description
1992 nî lūn-bûn
@nan
1992 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@ast
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@en
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@nl
type
label
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@ast
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@en
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@nl
prefLabel
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@ast
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@en
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@nl
P2093
P1476
Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180
@en
P2093
P2888
P304
P356
10.1111/1523-1747.EP12616580
P407
P577
1992-09-01T00:00:00Z
P5875
P6179
1031466129