Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities - Test2 - elhamkhani - TriplyDB

Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities

Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities

http://www.wikidata.org/entity/Q28213694

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Transcriptional activities of the zinc finger protein Zac are differentially controlled by DNA binding.Imprinted Zac1 in neural stem cells Regulation of cardiomyocyte Glut4 expression by ZAC1 Zac1 regulates astroglial differentiation of neural stem cells through Socs3.Zac1 regulates cell cycle arrest in neuronal progenitors via Tcf4 A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation A novel variation of PLAGL1 in Chinese patients with isolated ventricular septal defect Demonstration of all-or-none loss of imprinting in mRNA expression in single cells.Specific changes in the expression of imprinted genes in prostate cancer--implications for cancer progression and epigenetic regulation.Multitasking C2H2 zinc fingers link Zac DNA binding to coordinated regulation of p300-histone acetyltransferase activity.Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1 A new coactivator function for Zac1's C2H2 zinc finger DNA-binding domain in selectively controlling PCAF activity.Lot1 is a key element of the pituitary adenylate cyclase-activating polypeptide (PACAP)/cyclic AMP pathway that negatively regulates neuronal precursor proliferation.Resolution of infection promotes a state of dormancy and long survival of CD4 memory T cells.A tissue-specific promoter derived from a SINE retrotransposon drives biallelic expression of PLAGL1 in human lymphocytes Zac1 plays a key role in the development of specific neuronal subsets in the mouse cerebellum.LOT1 (ZAC1/PLAGL1) as member of an imprinted gene network does not harbor Silver-Russell specific variants.Members of the Plag gene family are expressed in complementary and overlapping regions in the developing murine nervous system.Differential expression pattern of ZAC in developing mouse and human pancreas.Tissue-specific imprinting of the ZAC/PLAGL1 tumour suppressor gene results from variable utilization of monoallelic and biallelic promoters.Chromosome 6q24-related diabetes mellitus.gene function during hepatoma cells proliferation

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Alternative splicing of the imprinted candidate tumor suppressor gene ZAC regulates its antiproliferative and DNA binding activities

http://www.wikidata.org/entity/Q28213694

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2001 nî lūn-bûn

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Alternative splicing of the im ...... ive and DNA binding activities

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P2860

Regulation of apoptosis and cell cycle arrest by Zac1, a novel zinc finger protein expressed in the pituitary gland and the brain.

hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer

Mutation and cancer: statistical study of retinoblastoma

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

LOT1 is a growth suppressor gene down-regulated by the epidermal growth factor receptor ligands and encodes a nuclear zinc-finger protein

The cell cycle control gene ZAC/PLAGL1 is imprinted--a strong candidate gene for transient neonatal diabetes

MRE-Binding transcription factor-1: weak zinc-binding finger domains 5 and 6 modulate the structure, affinity, and specificity of the metal-response element complex

Antioncogenes and human cancer.

Identification of a zinc-finger gene at 6q25: a chromosomal region implicated in development of many solid tumors

Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations

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