Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity
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BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma.Analysis of the vertebrate insulator protein CTCF-binding sites in the human genomeA screen for germline mutations in the gene encoding CCCTC-binding factor (CTCF) in familial non-BRCA1/BRCA2 breast cancerExpression analysis of candidate breast tumour suppressor genes on chromosome 16qGenome-wide studies of CCCTC-binding factor (CTCF) and cohesin provide insight into chromatin structure and regulationTINAGL1 and B3GALNT1 are potential therapy target genes to suppress metastasis in non-small cell lung cancer.Identification and analysis of pig chimeric mRNAs using RNA sequencing dataFrequent long-range epigenetic silencing of protocadherin gene clusters on chromosome 5q31 in Wilms' tumor.ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphismThe evolution of epigenetic regulators CTCF and BORIS/CTCFL in amniotes.Adaptive evolution in zinc finger transcription factors.CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancerClonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia.Chromatin architecture near a potential 3' end of the igh locus involves modular regulation of histone modifications during B-Cell development and in vivo occupancy at CTCF sites.Expression of a testis-specific form of Gal3st1 (CST), a gene essential for spermatogenesis, is regulated by the CTCF paralogous gene BORIS.The promoter methylation status and mRNA expression levels of CTCF and SIRT6 in sporadic breast cancerCTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulatorWidespread site-dependent buffering of human regulatory polymorphism.The functional significance of common polymorphisms in zinc finger transcription factorsEpigenetics of prostate cancer: beyond DNA methylationEnhancer alterations in cancer: a source for a cell identity crisis.Transcription factor-microRNA-target gene networks associated with ovarian cancer survival and recurrence.Conserved, developmentally regulated mechanism couples chromosomal looping and heterochromatin barrier activity at the homeobox gene A locusBORIS/CTCFL is an RNA-binding protein that associates with polysomes.Emerging landscape of oncogenic signatures across human cancers.Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activityTranscription factor BORIS (Brother of the Regulator of Imprinted Sites) directly induces expression of a cancer-testis antigen, TSP50, through regulated binding of BORIS to the promoterRestraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation.Chromatin insulators: a role in nuclear organization and gene expression.KIT Mutation and Loss of 14q May Be Sufficient for the Development of Clinically Symptomatic Very Low-Risk GIST.A Common Polymorphism within the IGF2 Imprinting Control Region Is Associated with Parent of Origin Specific Effects in Infantile HemangiomasThe dual specificity phosphatase 2 gene is hypermethylated in human cancer and regulated by epigenetic mechanismsCTCF-dependent chromatin insulator as a built-in attenuator of angiogenesisCoMEt: a statistical approach to identify combinations of mutually exclusive alterations in cancer.Genome-wide studies of the multi-zinc finger Drosophila Suppressor of Hairy-wing protein in the ovary.BORIS, brother of the regulator of imprinted sites, is aberrantly expressed in hepatocellular carcinomaElicitation of T cell responses to histologically unrelated tumors by immunization with the novel cancer-testis antigen, brother of the regulator of imprinted sites.Expression of the transcription factor CTCF in invasive breast cancer: a candidate gene located at 16q22.1.The three-dimensional cancer genome.Mutational analysis of GCMB, a parathyroid-specific transcription factor, in parathyroid adenoma of primary hyperparathyroidism.
P2860
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P2860
Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity
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2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
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2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@ast
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@en
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@nl
type
label
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@ast
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@en
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@nl
prefLabel
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@ast
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@en
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@nl
P2093
P3181
P1433
P1476
Tumor-associated zinc finger m ...... er tts DNA-binding specificity
@en
P2093
Akira Komiya
Andrew P Feinberg
Anne-Marie Cleton-Jansen
Annika Lindblom
Cees J Cornelisse
Chen-Feng Qi
Dmitri I Loukinov
Elena M Klenova
Elena M Pugacheva
Elna W Moerland
P3181
P407
P577
2002-01-01T00:00:00Z