Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells
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Phosphorylation of PEA-15 switches its binding specificity from ERK/MAPK to FADDProtein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic actionOn the Quest of Cellular Functions of PEA-15 and the Therapeutic OpportunitiesTaxol induces caspase-10-dependent apoptosisVanishin is a novel ubiquitinylated death-effector domain protein that blocks ERK activationPEA15 impairs cell migration and correlates with clinical features predicting good prognosis in neuroblastomaDeletion of PEA-15 in mice is associated with specific impairments of spatial learning abilities.Cord blood stem cell-mediated induction of apoptosis in glioma downregulates X-linked inhibitor of apoptosis protein (XIAP).Phosphoprotein enriched in astrocytes 15 kDa (PEA-15) reprograms growth factor signaling by inhibiting threonine phosphorylation of fibroblast receptor substrate 2alpha.DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas.Phosphoprotein enriched in astrocytes (PEA)-15: a potential therapeutic target in multiple disease states.mTOR controls FLIPS translation and TRAIL sensitivity in glioblastoma multiforme cellsPredominant antitumor effects by fully human anti-TRAIL-receptor 2 (DR5) monoclonal antibodies in human glioma cells in vitro and in vivo.Overexpression of the ped/pea-15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin actionPED/PEA-15 inhibits hydrogen peroxide-induced apoptosis in Ins-1E pancreatic beta-cells via PLD-1Identification of a novel AMPK-PEA15 axis in the anoikis-resistant growth of mammary cells.Expression of cellular FLICE-inhibitory protein and its association with p53 mutation in colon cancer.mTOR-independent translational control of the extrinsic cell death pathway by RalA.Caspase-mediated cell death in hematological malignancies: theoretical considerations, methods of assessment, and clinical implications.Regulating TRAIL receptor-induced cell death at the membrane : a deadly discussionClassifying ten types of major cancers based on reverse phase protein array profiles.K1 protein of human herpesvirus 8 suppresses lymphoma cell Fas-mediated apoptosisCisplatin restores TRAIL apoptotic pathway in glioblastoma-derived stem cells through up-regulation of DR5 and down-regulation of c-FLIP.Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis.PEA-15 modulates TNFalpha intracellular signaling in astrocytes.Clozapine impairs insulin action by up-regulating Akt phosphorylation and Ped/Pea-15 protein abundance.PED is overexpressed and mediates TRAIL resistance in human non-small cell lung cancer.Vitamin D3 signalling in the brain enhances the function of phosphoprotein enriched in astrocytes--15 kD (PEA-15).Effector CD4+ T cells generate intermediate caspase activity and cleavage of caspase-8 substrates.Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases.Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy.Mammalian initiator apoptotic caspases.Absence of caspase 8 and high expression of PED protect primitive neural cells from cell death.Use of APO2L/TRAIL with mTOR inhibitors in the treatment of glioblastoma multiforme.Negative regulation of multifunctional Ca2+/calmodulin-dependent protein kinases: physiological and pharmacological significance of protein phosphatases.The synergistic apoptotic interaction of Indole-3-Carbinol and Genistein with TRAIL on endometrial cancer cells.Alpha-CaMKII plays a critical role in determining the aggressive behavior of human osteosarcoma.In vitro sensitivity testing of minimally passaged and uncultured gliomas with TRAIL and/or chemotherapy drugs.A pilot study comparing protein expression in different segments of the normal colon and rectum and in normal colon versus adenoma in patients with Lynch syndromeImpact of human cytomegalovirus latent infection on myeloid progenitor cell gene expression.
P2860
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P2860
Tumor necrosis factor-related apoptosis-inducing ligand-induced death-inducing signaling complex and its modulation by c-FLIP and PED/PEA-15 in glioma cells
description
2002 nî lūn-bûn
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2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@ast
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@en
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@nl
type
label
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@ast
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@en
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@nl
prefLabel
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@ast
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@en
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@nl
P2093
P2860
P356
P1476
Tumor necrosis factor-related ...... and PED/PEA-15 in glioma cells
@en
P2093
Bao Feng Yang
Chang Xiao
Chunhai Hao
Francesco Beguinot
Neda Asadi
P2860
P304
P356
10.1074/JBC.M202946200
P407
P577
2002-07-12T00:00:00Z