Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway - Test2 - elhamkhani - TriplyDB

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

http://www.wikidata.org/entity/Q28217024

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E-cadherin/β-catenin complex and the epithelial barrier Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activity Regulation of the Wnt signaling pathway by disabled-2 (Dab2)Identification and characterization of a novel Dvl-binding protein that suppresses Wnt signalling pathway PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle HDAC6 is required for epidermal growth factor-induced beta-catenin nuclear localization The beta-catenin binding protein ICAT modulates androgen receptor activity PLAGL2 regulates Wnt signaling to impede differentiation in neural stem cells and gliomas GSK-3: tricks of the trade for a multi-tasking kinase Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.Wnt signaling: the good and the bad The links between axin and carcinogenesis The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich insulin response element Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays Toggling a conformational switch in Wnt/β-catenin signaling: regulation of Axin phosphorylation. The phosphorylation state of Axin controls its scaffold function in two Wnt pathway protein complexes Crosstalk between Wnt/β-catenin and Hedgehog/Gli signaling pathways in colon cancer and implications for therapy Role and regulation of β-catenin signaling during physiological liver growth GSK-3 as potential target for therapeutic intervention in cancer Microtubules depolymerization caused by the CK1 inhibitor IC261 may be not mediated by CK1 blockage Structure-Based Design of Potent and Selective CK1γ Inhibitors Wnt/β-catenin signaling in midbrain dopaminergic neuron specification and neurogenesis.Aberrant regulation of Wnt signaling in hepatocellular carcinoma N-cadherin-based adherens junction regulates the maintenance, proliferation, and differentiation of neural progenitor cells during development β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis A noncanonical sequence phosphorylated by casein kinase 1 in beta-catenin may play a role in casein kinase 1 targeting of important signaling proteins Casein kinase I epsilon enhances the binding of Dvl-1 to Frat-1 and is essential for Wnt-3a-induced accumulation of beta-catenin beta-catenin destruction complex: insights and questions from a structural perspective The β-catenin destruction complex Molecular association between beta-catenin degradation complex and Rac guanine exchange factor DOCK4 is essential for Wnt/beta-catenin signaling Interactions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1δ and CK1ε Regulation of Alzheimer's disease amyloid-beta formation by casein kinase I Casein kinase Iepsilon modulates the signaling specificities of dishevelled Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin The biology of the germ line in echinoderms Distinct Signaling Requirements for the Establishment of ESC Pluripotency in Late-Stage EpiSCs A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

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Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway

http://www.wikidata.org/entity/Q28217024

description

2002 nî lūn-bûn

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2002 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2002 թվականի մայիսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

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2002年论文

@wuu

name

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@ast

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@en

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@nl

type

label

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@ast

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@en

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@nl

prefLabel

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@ast

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@en

Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@nl

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Genes & Development

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Axin-mediated CKI phosphorylat ...... lar switch for the Wnt pathway

@en

P2093

Ada Hatzubai

http://www.w3.org/2001/XMLSchema#string

Etti Ben-Shushan

http://www.w3.org/2001/XMLSchema#string

Irit Alkalay

http://www.w3.org/2001/XMLSchema#string

Jens S Andersen

http://www.w3.org/2001/XMLSchema#string

Matthias Mann

http://www.w3.org/2001/XMLSchema#string

Sharon Amit

http://www.w3.org/2001/XMLSchema#string

Yaara Birman

http://www.w3.org/2001/XMLSchema#string

Yinon Ben-Neriah

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1.

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1066-76

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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1407546

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10.1101/GAD.230302

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9

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16

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2002-05-01T00:00:00Z

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11369735

http://www.w3.org/2001/XMLSchema#string

P698

12000790

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

186245

http://www.w3.org/2001/XMLSchema#string