Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR
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RNA sensors: novel regulators of gene expressionThe mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKRA translational rheostat for RFLAT-1 regulates RANTES expression in T lymphocytesTranscript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated regionSuppression of PKR promotes network excitability and enhanced cognition by interferon-γ-mediated disinhibitionImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionDistinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mREGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in miceBinding of superantigen toxins into the CD28 homodimer interface is essential for induction of cytokine genes that mediate lethal shockInhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNAYIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.A novel tumor-promoting function residing in the 5' non-coding region of vascular endothelial growth factor mRNATwo isoforms of the cold-inducible mRNA-binding protein RBM3 localize to dendrites and promote translationGene regulation by riboswitchesTranslational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory.Activation of the protein kinase PKR by short double-stranded RNAs with single-stranded tails.The protein kinase double-stranded RNA-dependent (PKR) enhances protection against disease cause by a non-viral pathogen.Double-stranded RNA-dependent protein kinase is involved in 2-methoxyestradiol-mediated cell death of osteosarcoma cells.Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birthRNA interference screen in primary human T cells reveals FLT3 as a modulator of IL-10 levels.Homeostatic defects in interleukin 18-deficient mice contribute to protection against the lethal effects of endotoxin.Translation control: a multifaceted regulator of inflammatory responseA PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domainsAnalysis of PKR activation using analytical ultracentrifugationThe ribosome filter redux.Pronounced virus-dependent activation drives exhaustion but sustains IFN-γ transcript levels.Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.The double-stranded RNA-dependent protein kinase differentially regulates insulin receptor substrates 1 and 2 in HepG2 cellsAlphavirus minus-strand synthesis and persistence in mouse embryo fibroblasts derived from mice lacking RNase L and protein kinase R.microRNA management of NK-cell developmental and functional programs.Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR.Regulation of innate immunity through RNA structure and the protein kinase PKR.Direct activation of ribosome-associated double-stranded RNA-dependent protein kinase (PKR) by deoxynivalenol, anisomycin and ricin: a new model for ribotoxic stress response inductionRNA helical imperfections regulate activation of the protein kinase PKR: effects of bulge position, size, and geometry.A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase.mRNA translation and protein synthesis: an analysis of different modelling methodologies and a new PBN based approach.A systems view of the protein expression process.Structural analysis of hepatitis C RNA genome using DNA microarraysMicroRNA-deficient NK cells exhibit decreased survival but enhanced functionThe double-stranded-RNA-binding motif: interference and much more.
P2860
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P2860
Human interferon-gamma mRNA autoregulates its translation through a pseudoknot that activates the interferon-inducible protein kinase PKR
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@ast
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@en
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@nl
type
label
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@ast
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@en
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@nl
prefLabel
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@ast
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@en
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@nl
P2093
P1433
P1476
Human interferon-gamma mRNA au ...... n-inducible protein kinase PKR
@en
P2093
Alexei Shir
Raymond Kaempfer
Yehuda Pel-Or
Yitzhak Ben-Asouli
Yona Banai
P304
P356
10.1016/S0092-8674(02)00616-5
P407
P577
2002-01-25T00:00:00Z