High bone density due to a mutation in LDL-receptor-related protein 5
about
sameAs
WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture riskSp1 and KLF15 regulate basal transcription of the human LRP5 geneWnt signaling in development and diseaseRapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strengthA form of the metabolic syndrome associated with mutations in DYRK1BBone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator functionAutosomal recessive familial exudative vitreoretinopathy is associated with mutations in LRP5.SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitorA novel mechanism for Wnt activation of canonical signaling through the LRP6 receptorMutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q.Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone densityPathogenesis of osteoporosis: concepts, conflicts, and prospectsLow-density lipoprotein receptor-related protein 5 (LRP5) is essential for normal cholesterol metabolism and glucose-induced insulin secretionCCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cellsA model for familial exudative vitreoretinopathy caused by LPR5 mutationsLrp5 functions in bone to regulate bone massWnt modulators in the biotech pipelineDistinct modes of inhibition by sclerostin on bone morphogenetic protein and Wnt signaling pathwaysThe Norrin/Frizzled4 signaling pathway in retinal vascular development and diseaseWnt/beta-catenin signaling: components, mechanisms, and diseasesFOXO1 orchestrates the bone-suppressing function of gut-derived serotoninWISP-1/CCN4 regulates osteogenesis by enhancing BMP-2 activityThe Wnt-dependent signaling pathways as target in oncology drug discoveryLrp5 controls bone formation by inhibiting serotonin synthesis in the duodenumOsteoimmunology: interactions of the bone and immune systemLinkage of osteoporosis to chromosome 20p12 and association to BMP2Modulating Dickkopf-1: A Strategy to Monitor or Treat Cancer?From disease to treatment: from rare skeletal disorders to treatments for osteoporosisWnts talking with the TGF-β superfamily: WISPers about modulation of osteoarthritisDiametrical diseases reflect evolutionary-genetic tradeoffs: Evidence from psychiatry, neurology, rheumatology, oncology and immunologyTargeting the Wnt pathways for therapiesFracture healing: mechanisms and interventionsNuclear receptors in bone physiology and diseasesWnt signaling strength regulates normal hematopoiesis and its deregulation is involved in leukemia developmentWNT signaling in bone development and homeostasisA new WNT on the bone: WNT16, cortical bone thickness, porosity and fracturesCellular signaling and biological functions of R-spondinsFriend or foe: high bone mineral density on routine bone density scanning, a review of causes and managementBeta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healingLRP5 and LRP6 are not required for protective antigen-mediated internalization or lethality of anthrax lethal toxin
P2860
Q21090209-89120157-FB2C-4A5D-B169-4D900C967D10Q21093395-DD5D7B8D-1B71-457E-AD58-D5D51B23B564Q21195871-F4F608DB-51D8-4125-863F-9F588008D812Q21563368-8FC6392B-B540-4216-80E9-CBE262AED373Q24297819-41CCCBE6-A359-4C79-97C1-4CD20F340C5BQ24299076-19F8FCF3-8B55-4846-8021-57D632E4DAC6Q24302508-1983EFFA-AE38-4B84-842F-6E191A26BCBDQ24303393-313671CF-01D1-413D-A2F6-79AD55276895Q24313393-FE3E7BE7-345C-4109-ABC5-790E43BE48C0Q24317292-5BA9A57E-81DD-4DD3-96ED-E91A084C86EDQ24531981-D8C44882-1327-4F3C-9B47-D46D6567A8CDQ24536164-1DEBABCD-1304-4107-821D-04140CD0A6F7Q24541297-80EA5D58-F184-47F0-970A-0BE2EEDAF23CQ24544140-B2CD2D7D-F80E-47AF-AF24-896C18F63B87Q24611293-785B28F6-E755-46C5-B524-8CA875DDAD58Q24615653-C26A41EB-B99E-4D46-9D35-113C1D82D1AFQ24618567-6184FE64-B588-4D8B-A3A5-2D454C34AA15Q24621990-4D6B9668-E018-421F-A092-CB919AFF4D65Q24627102-82E07772-6758-43D1-9AFA-C973DA9EABE2Q24630938-C349241F-8DBB-4E0C-9F0C-32295125D455Q24632551-011FC3F2-C9B3-4CC2-8170-7179015BD527Q24635850-011E1C4A-0186-4ACD-8C08-61E9AE8678C5Q24652979-A567DF6C-612C-4C27-BEF5-3C2682D7FECEQ24653502-06BA59E6-0393-4A6D-9470-880FD1B2A1D8Q24655113-66E273F2-1A9D-4655-96F6-EC172D65800DQ24792039-31294AC3-8ED5-4288-BD1E-A3FAA135C0B5Q26745556-8123FB22-07EF-4C19-94BF-DC54AF3B10ADQ26764854-15D1EE70-4CA2-4C6E-B596-8CC24EC3D834Q26775922-92FDB8A0-AD4A-46E8-8A08-8A5D9690A55AQ26782139-C7017501-626E-4634-AB26-5FF174B3DE03Q26821978-1F758A52-8174-428D-9D18-AA564AD8C665Q26851958-B7A9523B-5373-4A93-A2BB-6F6A01E27EBDQ26853017-6B2E9E2C-ED2F-4834-BA8A-FB947F278658Q26997109-24D8CD66-FDA8-4064-9754-67A24BFC824EQ27008570-F948C9E7-59C4-4B26-9EE9-FFA774AAB131Q27009420-DD63BB7A-8986-4F31-8C84-D0510057DE5FQ27023891-B134B38A-8CE9-4396-A572-0AEF0D046EC1Q27025982-DDD5E59D-CA48-47A2-845E-C88239D34D55Q27307639-860CABBC-3645-41DC-92DD-8D84C0A31710Q27319995-2F08B39F-0F25-4240-9B23-CA7061A07FBA
P2860
High bone density due to a mutation in LDL-receptor-related protein 5
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
High bone density due to a mutation in LDL-receptor-related protein 5
@ast
High bone density due to a mutation in LDL-receptor-related protein 5
@en
High bone density due to a mutation in LDL-receptor-related protein 5
@nl
type
label
High bone density due to a mutation in LDL-receptor-related protein 5
@ast
High bone density due to a mutation in LDL-receptor-related protein 5
@en
High bone density due to a mutation in LDL-receptor-related protein 5
@nl
prefLabel
High bone density due to a mutation in LDL-receptor-related protein 5
@ast
High bone density due to a mutation in LDL-receptor-related protein 5
@en
High bone density due to a mutation in LDL-receptor-related protein 5
@nl
P2093
P3181
P356
P1476
High bone density due to a mutation in LDL-receptor-related protein 5
@en
P2093
Anita Farhi
Dianqing Wu
Joseph Belsky
Junhao Mao
Karl Insogna
Lyle Mitzner
Lynn M Boyden
Mary A Mitnick
Richard P Lifton
P304
P3181
P356
10.1056/NEJMOA013444
P407
P577
2002-05-16T00:00:00Z