Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development
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Extracellular matrix as an inductive scaffold for functional tissue reconstructionFunctional and structural characterization of a heparanaseMelanoma Brain Metastasis: Mechanisms, Models, and MedicineHeparanase regulates thrombosis in vascular injury and stent-induced flow disturbanceMetastasis suppressor genes at the interface between the environment and tumor cell growthProteomics-based anticancer drug discovery and development.Small RNA interference-mediated gene silencing of heparanase abolishes the invasion, metastasis and angiogenesis of gastric cancer cellsScreening for anticoagulant heparan sulfate octasaccharides and fine structure characterization using tandem mass spectrometryRegulation of intracellular signaling by extracellular glycan remodeling.A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding.Significance of talin in cancer progression and metastasis.Extracellular matrix: a gatekeeper in the transition from dormancy to metastatic growthGlycosaminoglycans detection methods: Applications of mass spectrometry.Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase.Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.Heparanase regulates retention and proliferation of primitive Sca-1+/c-Kit+/Lin- cells via modulation of the bone marrow microenvironment.Anti-heparanase aptamers as potential diagnostic and therapeutic agents for oral cancer.Development of novel single-stranded nucleic acid aptamers against the pro-angiogenic and metastatic enzyme heparanase (HPSE1)Synthesized multiple antigenic polypeptide vaccine based on B-cell epitopes of human heparanase could elicit a potent antimetastatic effect on human hepatocellular carcinoma in vivo.Heparanase expression in nasopharyngeal carcinoma inversely correlates with patient survival.Heparanase plays a dual role in driving hepatocyte growth factor (HGF) signaling by enhancing HGF expression and activityThe role of heparanase in lymph node metastatic dissemination: dynamic contrast-enhanced MRI of Eb lymphoma in mice.In vitro and ex vivo evaluation of a multi-epitope heparinase vaccine for various malignancies.DNA methylation of heparanase promoter influences its expression and associated with the progression of human breast cancerTumor-derived syndecan-1 mediates distal cross-talk with bone that enhances osteoclastogenesis.The basement membrane matrix in malignancy.Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.Association of porcine heparanase and hyaluronidase 1 and 2 with reproductive and production traits in a landrace-duroc-yorkshire populationGenetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesisEffect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells.Overexpression of heparanase is associated with preeclampsia by inhibiting invasion of trophocytes.Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma.Heparanase: a target for drug discovery in cancer and inflammation.Advances in immunotherapy of multiple myeloma: from the discovery of tumor-associated antigens to clinical trials.Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myelomaSyndecan-1: a dynamic regulator of the myeloma microenvironment.The angiostatic activity of interferon-inducible protein-10/CXCL10 in human melanoma depends on binding to CXCR3 but not to glycosaminoglycan.Organ-specific heparan sulfate structural phenotypes.Inhibition of choriocarcinoma by Fe3O4-dextran-anti-β-human chorionic gonadotropin nanoparticles containing antisense oligodeoxynucleotide of heparanase.The GLI1 splice variant TGLI1 promotes glioblastoma angiogenesis and growth.
P2860
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P2860
Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development
description
2002 nî lūn-bûn
@nan
2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Mammalian heparanase: involvem ...... genesis and normal development
@ast
Mammalian heparanase: involvem ...... genesis and normal development
@en
Mammalian heparanase: involvem ...... genesis and normal development
@nl
type
label
Mammalian heparanase: involvem ...... genesis and normal development
@ast
Mammalian heparanase: involvem ...... genesis and normal development
@en
Mammalian heparanase: involvem ...... genesis and normal development
@nl
prefLabel
Mammalian heparanase: involvem ...... genesis and normal development
@ast
Mammalian heparanase: involvem ...... genesis and normal development
@en
Mammalian heparanase: involvem ...... genesis and normal development
@nl
P2093
P3181
P356
P1476
Mammalian heparanase: involvem ...... genesis and normal development
@en
P2093
Eyal Zcharia
Michael Elkin
Orit Goldshmidt
Ruth Atzmon
Tamar Peretz
Yael Friedmann
Zehava Rangini-Guatta
P3181
P356
10.1006/SCBI.2001.0420
P407
P577
2002-04-01T00:00:00Z