A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse
about
Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type MaroteauxFibroblast growth factor signaling in skeletal development and diseaseA pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationNon-synonymous FGD3 Variant as Positional Candidate for Disproportional Tall Stature Accounting for a Carcass Weight QTL (CW-3) and Skeletal Dysplasia in Japanese Black CattleSixteen years and counting: the current understanding of fibroblast growth factor receptor 3 (FGFR3) signaling in skeletal dysplasiasOsteocrin is a specific ligand of the natriuretic Peptide clearance receptor that modulates bone growthMice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling PathwayCardiac hypertrophy in transgenic rats expressing a dominant-negative mutant of the natriuretic peptide receptor B.Morphometrics and behavior of a wild Asian elephant exhibiting disproportionate dwarfismA novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux typeMutation of Npr2 leads to blurred tonotopic organization of central auditory circuits in miceA behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans.Regulation of axonal development by natriuretic peptide hormonesDexamethasone stimulates expression of C-type Natriuretic Peptide in chondrocytes.Protective effects of C-type natriuretic peptide on linear growth and articular cartilage integrity in a mouse model of inflammatory arthritisNovel functions of photoreceptor guanylate cyclases revealed by targeted deletionGastrointestinal tract disorder in natriuretic peptide receptor B gene mutant mice.Recent research on the growth plate: Recent insights into the regulation of the growth plateNovel mutations in natriuretic peptide receptor-2 gene underlie acromesomelic dysplasia, type maroteaux.Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasiaAn overgrowth disorder associated with excessive production of cGMP due to a gain-of-function mutation of the natriuretic peptide receptor 2 gene.The cn/cn dwarf mouse. Histomorphometric, ultrastructural, and radiographic study in mutants corresponding to human acromesomelic dysplasia Maroteaux type (AMDM).Genotype-Phenotype Correlation of 2q37 Deletions Including NPPC Gene Associated with Skeletal Malformations.Natriuretic peptides: their structures, receptors, physiologic functions and therapeutic applicationsEstablishment of a novel dwarf rat strain: cartilage calcification insufficient (CCI) rats.Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab -/- mice.High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.Natriuretic peptide metabolism, clearance and degradation.The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.Membrane guanylyl cyclase receptors: an updateGuanylyl cyclase structure, function and regulation.Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases.Nitric oxide, C-type natriuretic peptide and cGMP as regulators of endochondral ossification.Systemic administration of C-type natriuretic peptide as a novel therapeutic strategy for skeletal dysplasiasEmerging Roles of Natriuretic Peptides and their Receptors in Pathophysiology of Hypertension and Cardiovascular RegulationC-type natriuretic peptide (CNP) is a bifurcation factor for sensory neurons.Natriuretic peptide type C induces sperm attraction for fertilization in mouse.Skeletal Dysplasias: What Every Bone Health Clinician Needs to Know.Circulating osteocrin stimulates bone growth by limiting C-type natriuretic peptide clearance.CNP/NPR2 signaling maintains oocyte meiotic arrest in early antral follicles and is suppressed by EGFR-mediated signaling in preovulatory follicles.
P2860
Q24655560-8DA513BB-205E-48A2-B63C-2CF435A1A964Q26798215-A341E210-7B4E-4C12-A7EB-1832B566E50FQ26995910-FAD1F654-C055-4C98-B7C2-15FA954BA897Q27310532-AC270CCE-1ADC-4DE5-86A3-09D60A2A73BBQ28252023-5D51082F-AFE0-4DE1-ABF3-1919963FDD0DQ28254130-14805475-20BF-4A80-8C64-B70AE5F9C8BEQ28555004-1CF1B5D5-16EF-4843-8B7F-FB53F101C229Q28569799-05B6B130-6241-4D8A-877E-0688603D02E5Q28650350-ED6F2D5A-E3D2-4290-8FD6-CB5BB22C7AB1Q30359787-2C1BCF59-012E-486A-BE84-2D32A909F5A2Q30423186-2EEB90F6-E835-40BA-A929-AADEF6AC80DDQ30484715-E9AC492A-AB29-434A-9557-079B43241200Q30491080-00AA6A58-72B4-45CD-9D6B-346EBC8B4467Q33264124-6ACC3552-17C8-4B60-ADC2-EBB0C6B1F451Q33667772-3745E45B-BBCF-41C4-A20D-575D94638AA3Q33706821-19427300-F404-466D-AF9A-5E6DDEC905CAQ34033375-7CA4D3CE-2F76-4F7A-A0F2-D6D525EE0667Q34046963-9F03C930-5A90-4A5B-B8FE-14BB38C49D2FQ34301501-85EDF7D3-A9AA-4ED9-B4B1-0D3A1F953564Q34314761-FDC542EF-86C0-4282-9512-4A009A81EE50Q34369326-C18ADC01-3C08-48D7-B5BC-613AF0EB1A23Q34446997-D361FE1E-CA8B-48BE-92BA-AABF0CD3ED2FQ34785258-A98B3888-0E02-4219-86D3-8E1E57D39447Q34906050-4652FF7F-D4F9-407F-AD49-7B68CA66AD6EQ35594368-853F374F-6710-43C8-AE6B-410AE2F37D1EQ35600561-412E2845-4523-44F3-AC19-422D6FC2C80DQ35755147-78355786-2A9F-4E6C-B320-A244D0F9FF09Q35831469-9E985D62-F554-403B-8C60-4DECE9981503Q36119604-9BB76C2F-5FCE-41FF-8AD3-9D49CD2711FEQ36525043-581E03C4-6D99-48FA-99E6-405F5B9A442BQ36867727-A183DC18-B5BC-41CE-9FB1-E77A6D078700Q36867743-ECCEEEEC-7089-4BC0-A626-002297B73260Q37177999-82ABC9C9-F3ED-4D8A-B13B-4BEC8CD2DD96Q37244601-5F272572-3F1E-42BB-AF1C-283E196781CDQ37336602-A0BEA99D-9262-4EFC-8FA5-9885A74F964DQ37377219-42FA76CF-3E07-4F6E-9F4E-0A694A010E64Q37559002-3773E13F-7A6F-48BE-9D75-4750B66FC9B0Q38624569-7700488F-90CA-46B7-9E83-35237B6A522FQ47678461-84736366-3012-47BF-B0AC-EBC8A904B783Q48639486-7A9E53EE-28DF-4265-8CCA-2D2CDBEE4FE9
P2860
A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@ast
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@en
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@nl
type
label
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@ast
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@en
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@nl
prefLabel
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@ast
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@en
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@nl
P2860
P356
P1476
A loss-of-function mutation in ...... ionate dwarfism in cn/cn mouse
@en
P2093
Takehito Tsuji
Tetsuo Kunieda
P2860
P304
P356
10.1074/JBC.C500024200
P407
P577
2005-04-08T00:00:00Z