Lysyl oxidase is essential for hypoxia-induced metastasis
about
Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein responseThe Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cellsHypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transitionNuclear translocation of lysyl oxidase is promoted by interaction with transcription repressor p66βHIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activityDirect regulation of TWIST by HIF-1alpha promotes metastasisHypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic nicheMatrix crosslinking forces tumor progression by enhancing integrin signalingEvidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinomaHypoxic control of metastasisRole of nuclear receptors in breast cancer stem cellsImpacts of Ionizing Radiation on the Different Compartments of the Tumor MicroenvironmentInfluence of Immune Myeloid Cells on the Extracellular Matrix During Cancer MetastasisTargeting ECM Disrupts Cancer ProgressionEpigenetic Therapy for Solid Tumors: Highlighting the Impact of Tumor HypoxiaHIF-1α and growth plate development: what we really knowThe Effect of Hypoxia on Mesenchymal Stem Cell BiologyRole of hypoxia-inducible factors in breast cancer metastasisRemodelling the extracellular matrix in development and diseaseCancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasisTranscriptional control of cancer metastasisMolecular mechanism underlying lymphatic metastasis in pancreatic cancerRaf kinase inhibitory protein (RKIP) as a metastasis suppressor: regulation of signaling networks in cancerImaging tumor hypoxia to advance radiation oncologyDefining normoxia, physoxia and hypoxia in tumours-implications for treatment responseTumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces.In silico modelling of tumour margin diffusion and infiltration: review of current status.Pulmonary fibrosis: patterns and perpetratorsHIF1A overexpression is associated with poor prognosis in a cohort of 731 colorectal cancers.Stromal characteristics may hold the key to mammographic density: the evidence to dateThe role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapyMetastatic colonization by circulating tumour cellsThe ever-expanding role of HIF in tumour and stromal biologyMechanisms involved in breast cancer liver metastasisHypoxia-inducible factor 1 and breast cancer metastasisHepatic consequences of vascular adhesion protein-1 expressionLysyl oxidase: a lung adenocarcinoma biomarker of invasion and survivalMicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agentsCritical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancyLysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesis
P2860
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P2860
Lysyl oxidase is essential for hypoxia-induced metastasis
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Lysyl oxidase is essential for hypoxia-induced metastasis
@ast
Lysyl oxidase is essential for hypoxia-induced metastasis
@en
Lysyl oxidase is essential for hypoxia-induced metastasis
@nl
type
label
Lysyl oxidase is essential for hypoxia-induced metastasis
@ast
Lysyl oxidase is essential for hypoxia-induced metastasis
@en
Lysyl oxidase is essential for hypoxia-induced metastasis
@nl
prefLabel
Lysyl oxidase is essential for hypoxia-induced metastasis
@ast
Lysyl oxidase is essential for hypoxia-induced metastasis
@en
Lysyl oxidase is essential for hypoxia-induced metastasis
@nl
P2093
P3181
P356
P1433
P1476
Lysyl oxidase is essential for hypoxia-induced metastasis
@en
P2093
Amato J Giaccia
Christina Kong
Jen-Tsan Ashley Chi
Kevin L Bennewith
Monica Nicolau
Nadja Dornhöfer
Quynh-Thu Le
P2888
P304
P3181
P356
10.1038/NATURE04695
P407
P577
2006-04-27T00:00:00Z
P6179
1037985133