Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration - Test2 - elhamkhani - TriplyDB

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

http://www.wikidata.org/entity/Q28242708

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Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy Lentiviral vector gene therapy: effective and safe?Gene therapy for mucopolysaccharidosis T cell receptor gene therapy for cancer Adoptive T cell therapy for cancer in the clinic Gene therapy for severe combined immunodeficiency: are we there yet?Clinical development of gene therapy: results and lessons from recent successes Current and future alternative therapies for beta-thalassemia major Towards in vivo amplification: Overcoming hurdles in the use of hematopoietic stem cells in transplantation and gene therapy Adoptive immunotherapy for acute leukemia: New insights in chimeric antigen receptors Parkinson's disease: gene therapies CARs in chronic lymphocytic leukemia -- ready to drive Concise review: The magic act of generating induced pluripotent stem cells: many rabbits in the hat Hematopoietic stem cell gene therapy:assessing the relevance of preclinical models Gene therapy on the move Recent progress in satellite cell/myoblast engraftment -- relevance for therapy Protective Antiviral Immunity Conferred by a Nonintegrative Lentiviral Vector-Based Vaccine Identifying Cancer Driver Genes Using Replication-Incompetent Retroviral Vectors Gene therapy for hemophilia Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1 Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo Impact of hydrodynamic injection and phiC31 integrase on tumor latency in a mouse model of MYC-induced hepatocellular carcinoma Current progress and challenges in HIV gene therapy Gene therapy in the cornea: 2005--present.Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.Gene therapy model of X-linked severe combined immunodeficiency using a modified foamy virus vector Real-time definition of non-randomness in the distribution of genomic events Integration site selection by retroviral vectors: molecular mechanism and clinical consequences.Retroviral integration process in the human genome: is it really non-random? A new statistical approach.Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.Correction of murine Bernard-Soulier syndrome by lentivirus-mediated gene therapy.Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome.Comparison of insulators and promoters for expression of the Wiskott-Aldrich syndrome protein using lentiviral vectors.Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.Nonintegrating lentiviral vectors can effectively deliver ovalbumin antigen for induction of antitumor immunity.Gene-delivery systems for iPS cell generation.Lentiviral vector design for optimal T cell receptor gene expression in the transduction of peripheral blood lymphocytes and tumor-infiltrating lymphocytes.Cell- and gene-based therapeutic approaches for neurological deficits in mucopolysaccharidoses

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Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration

http://www.wikidata.org/entity/Q28242708

description

2006 nî lūn-bûn

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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2006年の論文

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Nature Biotechnology

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Hematopoietic stem cell gene t ...... lentiviral vector integration

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Clelia Di Serio

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Cynthia Bartholomae

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Fabrizio Benedicenti

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Francesca Sanvito

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Lucia Sergi Sergi

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Manfred Schmidt

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Maurilio Ponzoni

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The Hallmarks of Cancer

Gene ontology: tool for the unification of biology

Identifying biological themes within lists of genes with EASE

A census of human cancer genes

Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

Identification of oncogenes collaborating with p27Kip1 loss by insertional mutagenesis and high-throughput insertion site analysis.

Principles of tumor suppression

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687-96

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133759

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10.1038/NBT1216

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6

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24

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Christof von Kalle

Alessandro Ambrosi

Eugenio Montini

Claudio Doglioni

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2006-06-01T00:00:00Z

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7051066

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16732270

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