alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor
about
A family of heptahelical receptors with adhesion-like domains: a marriage between two super familiesLatrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilitiesHE6, a two-subunit heptahelical receptor associated with apical membranes of efferent and epididymal duct epitheliaAutoproteolysis of PIDD marks the bifurcation between pro-death caspase-2 and pro-survival NF-kappaB pathwayCleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell AdhesionVesicle exocytosis stimulated by alpha-latrotoxin is mediated by latrophilin and requires both external and stored Ca2+Molecular tinkering of G protein-coupled receptors: an evolutionary successA novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysisThe Genexpress IMAGE knowledge base of the human brain transcriptome: a prototype integrated resource for functional and computational genomicsalpha-Latrotoxin and its receptorsInsecticidal toxins from black widow spider venomLatrophilins function as heterophilic cell-adhesion molecules by binding to teneurins: regulation by alternative splicingHigh affinity neurexin binding to cell adhesion G-protein-coupled receptor CIRL1/latrophilin-1 produces an intercellular adhesion complexAlpha-latrotoxin stimulates a novel pathway of Ca2+-dependent synaptic exocytosis independent of the classical synaptic fusion machineryA stoichiometric complex of neurexins and dystroglycan in brainalpha-latrotoxin action probed with recombinant toxin: receptors recruit alpha-latrotoxin but do not transduce an exocytotic signalalpha-latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membraneThe Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney DiseaseOutside-in signaling--a brief review of GPCR signaling with a focus on the Drosophila GPCR familyMunc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteinsNovel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regionsType IV collagen is an activating ligand for the adhesion G protein-coupled receptor GPR126International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptorsActivation of myeloid cell-specific adhesion class G protein-coupled receptor EMR2 via ligation-induced translocation and interaction of receptor subunits in lipid raft microdomainsTargeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertilitySticky signaling--adhesion class G protein-coupled receptors take the stageNeurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unitA novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptorsFLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse developmentDREG, a developmentally regulated G protein-coupled receptor containing two conserved proteolytic cleavage sitesThe G protein-coupled receptor CL1 interacts directly with proteins of the Shank familyETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamilyThe Optimedin gene is a downstream target of Pax6Definition of Munc13-homology-domains and characterization of a novel ubiquitously expressed Munc13 isoformNorepinephrine exocytosis stimulated by alpha-latrotoxin requires both external and stored Ca2+ and is mediated by latrophilin, G proteins and phospholipase CPrediction of G Protein-Coupled Receptors with SVM-Prot Features and Random ForestThe latrophilin family: multiply spliced G protein-coupled receptors with differential tissue distribution.Genetic analysis of alpha-latrotoxin receptors reveals functional interdependence of CIRL/latrophilin 1 and neurexin 1 alpha.
P2860
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P2860
alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@ast
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@en
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@nl
type
label
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@ast
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@en
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@nl
prefLabel
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@ast
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@en
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@nl
P2093
P3181
P1433
P1476
alpha-Latrotoxin stimulates ex ...... nal G-protein-coupled receptor
@en
P2093
A G Petrenko
A N Plotnikov
A R Little
K V Salnikow
M A Bittner
O G Chepurny
V G Krasnoperov
P304
P3181
P356
10.1016/S0896-6273(00)80332-3
P407
P577
1997-06-01T00:00:00Z