A knowledge-based energy function for protein-ligand, protein-protein, and protein-DNA complexes
about
A structure-based benchmark for protein-protein binding affinityWeb-based toolkits for topology prediction of transmembrane helical proteins, fold recognition, structure and binding scoring, folding-kinetics analysis and comparative analysis of domain combinationsSupport vector regression scoring of receptor-ligand complexes for rank-ordering and virtual screening of chemical librariesComputational structural analysis: multiple proteins bound to DNAAccessible high-throughput virtual screening molecular docking software for students and educatorsDevelopment of QSAR-Improved Statistical Potential for the Structure-Based Analysis of ProteinPeptide Binding Affinities.Optimizing scoring function of protein-nucleic acid interactions with both affinity and specificity.Ultra-fast evaluation of protein energies directly from sequenceA Bayesian statistical approach of improving knowledge-based scoring functions for protein-ligand interactions.NPDock: a web server for protein-nucleic acid dockingQuantitative prediction of protein-protein binding affinity with a potential of mean force considering volume correction.Trends in template/fragment-free protein structure predictionNCACO-score: an effective main-chain dependent scoring function for structure modelingWater PMF for predicting the properties of water molecules in protein binding site.Protein-DNA docking with a coarse-grained force field.DrugScorePPI knowledge-based potentials used as scoring and objective function in protein-protein docking.Exploiting residue-level and profile-level interface propensities for usage in binding sites prediction of proteins.Computational modeling of protein mutant stability: analysis and optimization of statistical potentials and structural features reveal insights into prediction model development.Identification of DNA-binding protein target sequences by physical effective energy functions: free energy analysis of lambda repressor-DNA complexes.Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies.Targeting the dimerization of epidermal growth factor receptors with small-molecule inhibitors.BioDrugScreen: a computational drug design resource for ranking molecules docked to the human proteomeThe cis conformation of proline leads to weaker binding of a p53 peptide to MDM2 compared to trans.Target-specific support vector machine scoring in structure-based virtual screening: computational validation, in vitro testing in kinases, and effects on lung cancer cell proliferationSPA-LN: a scoring function of ligand-nucleic acid interactions via optimizing both specificity and affinity.Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnosticsAn efficient algorithm for improving structure-based prediction of transcription factor binding sitesStructure-based prediction of DNA-binding proteins by structural alignment and a volume-fraction corrected DFIRE-based energy functionPredicting target DNA sequences of DNA-binding proteins based on unbound structures.Binding site multiplicity with fatty acid ligands: implications for the regulation of PKR kinase autophosphorylation with palmitateAdvances and challenges in protein-ligand dockingSanjeevini: a freely accessible web-server for target directed lead molecule discoveryA structural-based strategy for recognition of transcription factor binding sites.The unorthodox SNAP50 zinc finger domain contributes to cooperative promoter recognition by human SNAPC.Structure-based prediction of RNA-binding domains and RNA-binding sites and application to structural genomics targets.Four-body atomic potential for modeling protein-ligand binding affinity: application to enzyme-inhibitor binding energy prediction.Predicting DNA-binding proteins and binding residues by complex structure prediction and application to human proteome.Challenges, applications, and recent advances of protein-ligand docking in structure-based drug design.Structure-based lead discovery for protein kinase C zeta inhibitor design by exploiting kinase-inhibitor complex crystal structure data and potential therapeutics for preterm labour.How structure defines affinity in protein-protein interactions.
P2860
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P2860
A knowledge-based energy function for protein-ligand, protein-protein, and protein-DNA complexes
description
2005 nî lūn-bûn
@nan
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@ast
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@en
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@nl
type
label
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@ast
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@en
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@nl
prefLabel
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@ast
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@en
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@nl
P3181
P356
P1476
A knowledge-based energy funct ...... ein, and protein-DNA complexes
@en
P2093
Qianqian Zhu
P304
P3181
P356
10.1021/JM049314D
P407
P577
2005-04-07T00:00:00Z