Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding
about
N-Terminal Acetylation-Targeted N-End Rule Proteolytic System: The Ac/N-End Rule PathwayN-terminal modifications of cellular proteins: The enzymes involved, their substrate specificities and biological effectsAmyloid-associated activity contributes to the severity and toxicity of a prion phenotypeBiochemical and cellular analysis of Ogden syndrome reveals downstream Nt-acetylation defectsCrystal Structure of the Golgi-Associated Human Nα-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific AcetylationThe biological functions of Naa10 - From amino-terminal acetylation to human diseaseNaa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion.New roles for old modifications: emerging roles of N-terminal post-translational modifications in development and disease.Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo.NAA10 mutation causing a novel intellectual disability syndrome with Long QT due to N-terminal acetyltransferase impairment.Molecular identification and functional characterization of the first Nα-acetyltransferase in plastids by global acetylome profiling.Positional proteomics reveals differences in N-terminal proteoform stability.Expanding the Phenotype Associated with NAA10-Related N-Terminal Acetylation DeficiencyN-terminal acetylation promotes synaptonemal complex assembly in C. elegans.Proteomic and genomic characterization of a yeast model for Ogden syndrome.A Role for Human N-alpha Acetyltransferase 30 (Naa30) in Maintaining Mitochondrial Integrity.Microscopy-based Saccharomyces cerevisiae complementation model reveals functional conservation and redundancy of N-terminal acetyltransferases.Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway.A dominant-negative mutant inhibits multiple prion variants through a common mechanism.Stress response of a marine ammonia-oxidizing archaeon informs physiological status of environmental populations.Molecular determinants of the N-terminal acetyltransferase Naa60 anchoring to the Golgi membrane.Structural determinants and cellular environment define processed actin as the sole substrate of the N-terminal acetyltransferase NAA80.NAA80 is actin's N-terminal acetyltransferase and regulates cytoskeleton assembly and cell motility.[PIN+]ing down the mechanism of prion appearance.Investigating the functionality of a ribosome-binding mutant of NAA15 using Saccharomyces cerevisiae.Minimotifs dysfunction is pervasive in neurodegenerative disorders
P2860
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P2860
Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding
description
2014 nî lūn-bûn
@nan
2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Loss of amino-terminal acetyla ...... ulating global protein folding
@ast
Loss of amino-terminal acetyla ...... ulating global protein folding
@en
Loss of amino-terminal acetyla ...... ulating global protein folding
@nl
type
label
Loss of amino-terminal acetyla ...... ulating global protein folding
@ast
Loss of amino-terminal acetyla ...... ulating global protein folding
@en
Loss of amino-terminal acetyla ...... ulating global protein folding
@nl
prefLabel
Loss of amino-terminal acetyla ...... ulating global protein folding
@ast
Loss of amino-terminal acetyla ...... ulating global protein folding
@en
Loss of amino-terminal acetyla ...... ulating global protein folding
@nl
P2093
P2860
P3181
P356
P1476
Loss of amino-terminal acetyla ...... ulating global protein folding
@en
P2093
Brian K Mannakee
Ryan N Gutenkunst
Tricia R Serio
William M Holmes
P2860
P2888
P3181
P356
10.1038/NCOMMS5383
P407
P577
2014-07-15T00:00:00Z
P5875
P6179
1050785210