The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species
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The human lysyl-tRNA synthetase gene encodes both the cytoplasmic and mitochondrial enzymes by means of an unusual alternative splicing of the primary transcriptKeeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPasesdUTPase: the frequently overlooked enzyme encoded by many retrovirusesPhosphorylation adjacent to the nuclear localization signal of human dUTPase abolishes nuclear import: structural and mechanistic insightsHuman mitochondrial 5'-deoxyribonucleotidase. Overproduction in cultured cells and functional aspectsRegulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damageArginine deficiency in preconfluent intestinal Caco-2 cells modulates expression of proteins involved in proliferation, apoptosis, and heat shock response.Calpain-catalyzed proteolysis of human dUTPase specifically removes the nuclear localization signal peptide.Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivoAlteration of nucleotide metabolism: a new mechanism for mitochondrial disorders.Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration.Effects of vaccinia virus uracil DNA glycosylase catalytic site and deoxyuridine triphosphatase deletion mutations individually and together on replication in active and quiescent cells and pathogenesis in mice.Uracil within DNA: an actor of antiviral immunity.Phosphorylation of herpes simplex virus 1 dUTPase upregulated viral dUTPase activity to compensate for low cellular dUTPase activity for efficient viral replication.p53 in the mitochondria, as a trans-acting protein, provides error-correction activities during the incorporation of non-canonical dUTP into DNA.Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectivelyMitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).Thymidine phosphorylase deficiency causes MNGIE: an autosomal recessive mitochondrial disorder.Developmental regulation of dUTPase in Drosophila melanogaster.Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3.Targeting Nucleotide Biosynthesis: A Strategy for Improving the Oncolytic Potential of DNA Viruses.Mitochondrial and chloroplastic targeting signals of NADP+-dependent isocitrate dehydrogenase.Characterization of deoxyuridine 5'-triphosphate nucleotidohydrolase from Trypanosoma cruzi.Altered active site flexibility and a structural metal-binding site in eukaryotic dUTPase: kinetic characterization, folding, and crystallographic studies of the homotrimeric Drosophila enzyme.Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation.Molecular cloning, partial genomic structure and functional characterization of succinic semialdehyde dehydrogenase genes from the parasitic insects Lucilia cuprina and Ctenocephalides felis.Molecular cloning of geranyl diphosphate synthase and compartmentation of monoterpene synthesis in plant cells.dUTPase expression correlates with cell division potential in Drosophila melanogaster.Cysteine residues contribute to the dimerization and enzymatic activity of human nuclear dUTP nucleotidohydrolase (nDut)
P2860
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P2860
The human dUTPase gene encodes both nuclear and mitochondrial isoforms. Differential expression of the isoforms and characterization of a cDNA encoding the mitochondrial species
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
The human dUTPase gene encodes ...... ding the mitochondrial species
@ast
The human dUTPase gene encodes ...... ding the mitochondrial species
@en
The human dUTPase gene encodes ...... ding the mitochondrial species
@nl
type
label
The human dUTPase gene encodes ...... ding the mitochondrial species
@ast
The human dUTPase gene encodes ...... ding the mitochondrial species
@en
The human dUTPase gene encodes ...... ding the mitochondrial species
@nl
prefLabel
The human dUTPase gene encodes ...... ding the mitochondrial species
@ast
The human dUTPase gene encodes ...... ding the mitochondrial species
@en
The human dUTPase gene encodes ...... ding the mitochondrial species
@nl
P2860
P356
P1476
The human dUTPase gene encodes ...... ding the mitochondrial species
@en
P2093
R D Ladner
S J Caradonna
P2860
P304
P356
10.1074/JBC.272.30.19072
P407
P577
1997-07-25T00:00:00Z