Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
about
PBX2 and PBX3, new homeobox genes with extensive homology to the human proto-oncogene PBX1MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell linesCloning and expression of a new HOXC6 transcript encoding a repressing proteinTAL2, a helix-loop-helix gene activated by the (7;9)(q34;q32) translocation in human T-cell leukemiaBAZF, a novel Bcl6 homolog, functions as a transcriptional repressorThe HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genesHEX: a novel homeobox gene expressed during haematopoiesis and conserved between mouse and humanFusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocationGene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223Identification of a novel vertebrate homeobox gene expressed in haematopoietic cellsAbrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesisG1/S transcriptional networks modulated by the HOX11/TLX1 oncogene of T-cell acute lymphoblastic leukemiaHOXB7 constitutively activates basic fibroblast growth factor in melanomasMeis1, a PBX1-related homeobox gene involved in myeloid leukemia in BXH-2 micePbx3 deficiency results in central hypoventilationInhibition of DLX-7 homeobox gene causes decreased expression of GATA-1 and c-myc genes and apoptosisAltered HOX and WNT7A expression in human lung cancerRefined physical map of the human PAX2/HOX11/NFKB2 cancer gene region at 10q24 and relocalization of the HPV6AI1 viral integration site to 14q13.3-q21.1Cooperative DNA-binding and sequence-recognition mechanism of aristaless and clawlessHOX11 interacts with CTF1 and mediates hematopoietic precursor cell immortalizationTALE homeoproteins as HOX11-interacting partners in T-cell leukemiaAnalysis of the V(D)J recombination efficiency at lymphoid chromosomal translocation breakpointsIdentification and characterization of SEB, a novel protein that binds to the acute undifferentiated leukemia-associated protein SETHRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2AA conserved C-terminal domain in PBX increases DNA binding by the PBX homeodomain and is not a primary site of contact for the YPWM motif of HOXA1Association of the TLX-2 homeodomain and 14-3-3eta signaling proteinsThe nuclear oncoprotein TLX1/HOX11 associates with pericentromeric satellite 2 DNA in leukemic T-cellsImmortality of cell lines: challenges and advantages of establishmentA new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemiasActivation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemiaFormation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3The HoxB1 hexapeptide is a prefolded domain: implications for the Pbx1/Hox interactionA novel pathogenesis of megacolon in Ncx/Hox11L.1 deficient miceProper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1cDNA cloning and expression of rat homeobox gene, Hex, and functional characterization of the proteinMouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3aThymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphomaRnx deficiency results in congenital central hypoventilationIdentification of an optimal Ncx binding sequence required for transcriptional activationHoxB8 requires its Pbx-interaction motif to block differentiation of primary myeloid progenitors and of most cell line models of myeloid differentiation.
P2860
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P2860
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
description
1991 nî lūn-bûn
@nan
1991 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@ast
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@en
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@nl
type
label
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@ast
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@en
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@nl
prefLabel
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@ast
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@en
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@nl
P2093
P3181
P356
P1433
P1476
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia
@en
P2093
C W Roberts
S J Korsmeyer
P3181
P356
10.1126/SCIENCE.1676542
P407
P577
1991-07-05T00:00:00Z