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DNA polymerase hybrids derived from the family-B enzymes of Pyrococcus furiosus and Thermococcus kodakarensis: improving performance in the polymerase chain reactionComparison of the xylose reductase-xylitol dehydrogenase and the xylose isomerase pathways for xylose fermentation by recombinant Saccharomyces cerevisiaeQuantifying the adaptive potential of an antibiotic resistance enzymeDNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolutionIn the light of directed evolution: pathways of adaptive protein evolutionFundamental challenges in mechanistic enzymology: progress toward understanding the rate enhancements of enzymesDNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolutionDirected evolution of protein enzymes using nonhomologous random recombinationEvolvability is a selectable traitThe genetic code constrains yet facilitates Darwinian evolutionExploring protein fitness landscapes by directed evolutionIn vitro selection and evolution of functional proteins by using ribosome displaySimultaneous optimization of enzyme activity and quaternary structure by directed evolutionSubstrate-assisted catalysis: molecular basis and biological significanceIn vitro evolution of single-chain antibodies using mRNA displayAnticipatory evolution and DNA shufflingTriplet nucleotide removal at random positions in a target gene: the tolerance of TEM-1 beta-lactamase to an amino acid deletion.Correcting errors in synthetic DNA through consensus shuffling.The evolutionary value of recombination is constrained by genome modularity.Directed evolution strategies for improved enzymatic performanceNucleotide exchange and excision technology (NExT) DNA shuffling: a robust method for DNA fragmentation and directed evolutionRAISE: a simple and novel method of generating random insertion and deletion mutationsNothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological ProcessIntegrated (Meta) Genomic and Synthetic Biology Approaches to Develop New BiocatalystsWhy reinvent the wheel? Building new proteins based on ready-made partsApplications of Yeast Surface Display for Protein EngineeringTo get what we aim for--progress in diversity generation methodsInsights into cytokine-receptor interactions from cytokine engineeringExpanding the scope of site-specific recombinases for genetic and metabolic engineeringLibrary methods for structural biology of challenging proteins and their complexesA bulged stem-loop structure in the 3' untranslated region of the genome of the coronavirus mouse hepatitis virus is essential for replicationA structural view of evolutionary divergenceDirected in vitro evolution and crystallographic analysis of a peptide-binding single chain antibody fragment (scFv) with low picomolar affinityGenetic and Structural Characterization of an L201P Global Suppressor Substitution in TEM-1 β-LactamaseDirected evolution of copper nitrite reductase to a chromogenic reductantJanus: Prediction and Ranking of Mutations Required for Functional Interconversion of EnzymesDirected evolution of Mycobacterium tuberculosis β-lactamase reveals gatekeeper residue that regulates antibiotic resistance and catalytic efficiencyCrystal structure determination and mutagenesis analysis of the ene reductase NCRAn improved monomeric infrared fluorescent protein for neuronal and tumour brain imagingRedesigning the substrate specificity of an enzyme by cumulative effects of the mutations of non-active site residues
P2860
Q21131094-65BE01BE-5226-4AA9-84DE-A8378FF7AAD6Q21246025-790130B5-2EEC-43DF-81FB-098F899A582BQ21563371-F7F1DCC8-9127-4D56-BBC7-6C769BD8712DQ21563643-57CAFE77-345E-4D9E-96BC-159B04A541FEQ22066327-EF415A4F-FB69-4556-9ADE-09550FD031E0Q24289386-165E4A62-D81C-4886-B557-89E1D2E5A34EQ24562755-467EA6B1-6DB6-4A2B-81DE-0AB1FF4AA5BDQ24563994-674B438F-BA98-46CA-9138-4233D894285DQ24564104-3C095FB7-51A8-4119-81BC-FF3BF169215EQ24629982-2AC416F4-A9D9-4E47-9FDA-0B831707A64BQ24630945-87F2EA7A-EED9-4244-A72D-01595F9CDFA9Q24643887-6327B6E4-D0A6-457A-9B0A-DC3B7A1C3845Q24646681-F71C8EC1-3BE7-47A6-A369-A47EE6AC1143Q24672568-5A974492-E1EA-4E85-AFED-EF092C6F55D4Q24672839-C6C1C445-2966-4A1B-89D8-6BC02565C78AQ24792599-F59386C9-1BF5-4FC1-A294-69221C6F9177Q24804616-386D140C-7696-4535-AB26-D3B825C4C001Q24805929-5F913989-D83C-4669-A167-29942F6A1ADBQ24814667-28A2A06D-B7D6-4A70-80E0-550A54674AFAQ24815563-A7F7263C-B71E-49FD-B485-18211655F344Q24816006-2B92EB7E-37FD-4E5A-998A-06AA29892BFAQ25256082-95DCAF79-C68F-4F07-80AC-AF3700080255Q26315280-5F41E86C-F5D8-4473-A155-F1D89B6D35E6Q26752345-CBB68AE3-1087-4709-A446-8452C082C3A3Q26773046-EB8B05B7-EABA-419F-AF48-0AF7AE8A62B3Q26823830-5F6ACB25-832A-438A-BE26-FDADD081C694Q26851750-4D0E8119-C5DA-4AD8-BEA1-9DD9290A663EQ26852703-19ECF68B-7EAE-4A54-BA0C-C5290361446FQ26995224-4AE545C5-A9DE-4612-8838-B2863F9182B0Q27008422-6AEBC303-B48B-45E7-ABB1-3C21CD00D249Q27480879-2AFC28C6-7E85-46CC-A3D6-42B4965AF564Q27620081-13A761BB-E5F1-40ED-9E06-255451D315FBQ27643060-F0018DE0-15F5-4CB7-BDA1-015CF7940D98Q27652316-B0A1A3ED-487D-4D8F-A4A7-5275D8FD58A9Q27659029-5E6F0277-FEB0-4D2F-8BA5-3AED795583C3Q27676283-1C27AACA-DCF4-498D-B004-50D2FB80EBF7Q27679915-F6EFA04F-7662-46D4-9529-856C9A3A0B9DQ27682645-233FD63F-C5EA-4879-AECE-159CD98DB3CDQ27683806-D443EA34-CAFD-4C42-8602-B26B91C22415Q27766665-82D5DD75-C3DD-4FE5-9FE9-FB820613365E
P2860
description
1994 nî lūn-bûn
@nan
1994 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Rapid evolution of a protein in vitro by DNA shuffling
@ast
Rapid evolution of a protein in vitro by DNA shuffling
@en
Rapid evolution of a protein in vitro by DNA shuffling
@nl
type
label
Rapid evolution of a protein in vitro by DNA shuffling
@ast
Rapid evolution of a protein in vitro by DNA shuffling
@en
Rapid evolution of a protein in vitro by DNA shuffling
@nl
prefLabel
Rapid evolution of a protein in vitro by DNA shuffling
@ast
Rapid evolution of a protein in vitro by DNA shuffling
@en
Rapid evolution of a protein in vitro by DNA shuffling
@nl
P3181
P356
P1433
P1476
Rapid evolution of a protein in vitro by DNA shuffling
@en
P2888
P304
P3181
P356
10.1038/370389A0
P407
P577
1994-08-04T00:00:00Z
P5875
P6179
1030993177