Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
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New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseasesRole of osteopontin in regulating hepatic inflammatory responses and toxic liver injuryOsteopontin undergoes polymerization in vivo and gains chemotactic activity for neutrophils mediated by integrin alpha9beta1.The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver diseasePolymeric osteopontin employs integrin alpha9beta1 as a receptor and attracts neutrophils by presenting a de novo binding siteThe role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in miceAnimals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: pathophysiology, translational relevance, and challengesMechanisms of immune-mediated liver injury.Secreted osteopontin is highly polymerized in human airways and fragmented in asthmatic airway secretionsToll-like receptors in the pathogenesis of alcoholic liver disease.Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation.PAPSS2 promotes alkaline phosphates activity and mineralization of osteoblastic MC3T3-E1 cells by crosstalk and Smads signal pathways.Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice.¹H and ³¹P NMR lipidome of ethanol-induced fatty liver.Inhibition of type I natural killer T cells by retinoids or following sulfatide-mediated activation of type II natural killer T cells attenuates alcoholic liver disease in mice.Osteopontin expression is associated with hepatopathologic changes in Schistosoma japonicum infected mice.Gut microbiota and inflammation.Plasma osteopontin is a biomarker for the severity of alcoholic liver cirrhosis, not for hepatocellular carcinoma screeningFarnesoid X receptor activation promotes cell proliferation via PDK4-controlled metabolic reprogramming.Osteopontin, an oxidant stress sensitive cytokine, up-regulates collagen-I via integrin α(V)β(3) engagement and PI3K/pAkt/NFκB signaling.Role of neutrophils in acute inflammatory liver injury.Potential relationship between hepatobiliary osteopontin and peroxisome proliferator-activated receptor alpha expression following ethanol-associated hepatic injury in vivo and in vitroPathophysiological role of osteopontin in hepatic inflammation, toxicity, and cancer.Therapeutic targets for cholestatic liver injuryRole of neutrophils in the pathogenesis of acute inflammatory liver injury.Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium.Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.Pathogenesis of alcoholic liver disease: the role of nuclear receptors.Hepatic neutrophil infiltration in the pathogenesis of alcohol-induced liver injury.Osteopontin binding to lipopolysaccharide lowers tumor necrosis factor-α and prevents early alcohol-induced liver injury in mice.Alcoholic liver disease and the gut-liver axis.Osteopontin: Versatile modulator of liver diseases.Targeting inflammation for the treatment of alcoholic liver disease.Alcoholic Steatosis in Different Strains of Rat: A Comparative StudyExposure to cypermethrin and mancozeb alters the expression profile of THBS1, SPP1, FEZ1 and GPNMB in human peripheral blood mononuclear cells.Roles of phosphatidylinositol 3-kinase and osteopontin in steatosis and aminotransferase release by hepatocytes treated with methionine-choline-deficient medium.Modulation of infection-mediated migration of neutrophils and CXCR2 trafficking by osteopontin.Role of bile acids in liver injury and regeneration following acetaminophen overdose.Lipidomic changes in rat liver after long-term exposure to ethanol.Osteopontin activates mesenchymal stem cells to repair skin wound.
P2860
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P2860
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@ast
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@en
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@nl
type
label
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@ast
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@en
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@nl
prefLabel
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@ast
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@en
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@nl
P2093
P1476
Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis
@en
P2093
Atrayee Banerjee
Elizabeth Wellberg
Rachel McRee
Shashi K Ramaiah
Udayan M Apte
P356
10.1016/J.TAAP.2004.12.018
P407
P577
2005-08-22T00:00:00Z