The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death - Test2 - elhamkhani - TriplyDB

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

http://www.wikidata.org/entity/Q28250070

about

Translocation of human ribosomal protein S3 to sites of DNA damage is dependant on ERK-mediated phosphorylation following genotoxic stress Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase A quarter century of granzymes Trex1 prevents cell-intrinsic initiation of autoimmunity Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2 The crystal structure of TREX1 explains the 3' nucleotide specificity and reveals a polyproline II helix for protein partnering Structure of the dimeric exonuclease TREX1 in complex with DNA displays a proline-rich binding site for WW Domains Structural and biochemical studies of TREX1 inhibition by metals. Identification of a new active histidine conserved in DEDDh exonucleases Defects in DNA degradation revealed in crystal structures of TREX1 exonuclease mutations linked to autoimmune disease Structural and functional analysis of novel human cytochrome C targets in apoptosis New Arabidopsis thaliana cytochrome c partners: a look into the elusive role of cytochrome c in programmed cell death in plants DNase 2 is the main DNA-degrading enzyme of the stratum corneum TLR ligands up-regulate Trex1 expression in murine conventional dendritic cells through type I Interferon and NF-κB-dependent signaling pathways The migraine-stroke connection: A genetic perspective.The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function.Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha.The SET complex acts as a barrier to autointegration of HIV-1 Immunohistochemical analysis of oxidative stress and DNA repair proteins in normal mammary and breast cancer tissues.Aicardi-Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion New roles for the major human 3'-5' exonuclease TREX1 in human disease.RNaseH2 mutants that cause Aicardi-Goutieres syndrome are active nucleases Granzyme A activates another way to die Conserved BK channel-protein interactions reveal signals relevant to cell death and survival.NM23-H1 expression of head and neck squamous cell carcinoma in association with the response to cisplatin treatment.The DNA sensor, cyclic GMP-AMP synthase, is essential for induction of IFN-β during Chlamydia trachomatis infection.Evolution of a tumor-like lesion in cerebroretinal vasculopathy and TREX1 mutation.The 3'-5' DNA exonuclease TREX1 directly interacts with poly(ADP-ribose) polymerase-1 (PARP1) during the DNA damage response.Death by a thousand cuts: granzyme pathways of programmed cell death Gaining a foothold: how HIV avoids innate immune recognition.Functional modulation of the metastatic suppressor Nm23-H1 by oncogenic viruses Granzymes and perforin in solid organ transplant rejection.Genetics of Vascular Dementia.Recent Insights into the Control of Human Papillomavirus (HPV) Genome Stability, Loss, and Degradation.Dominant mutation of the TREX1 exonuclease gene in lupus and Aicardi-Goutieres syndrome.Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.Type I interferon and systemic lupus erythematosus.The TREX1 exonuclease R114H mutation in Aicardi-Goutières syndrome and lupus reveals dimeric structure requirements for DNA degradation activity.Heterozygous mutations in TREX1 cause familial chilblain lupus and dominant Aicardi-Goutieres syndrome.The N-terminal Set-β Protein Isoform Induces Neuronal Death

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P2860

The exonuclease TREX1 is in the SET complex and acts in concert with NM23-H1 to degrade DNA during granzyme A-mediated cell death

http://www.wikidata.org/entity/Q28250070

description

2006 nî lūn-bûn

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2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2006 թվականի հուլիսին հրատարակված գիտական հոդված

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2006年の論文

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The exonuclease TREX1 is in th ...... granzyme A-mediated cell death

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The exonuclease TREX1 is in th ...... granzyme A-mediated cell death

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The exonuclease TREX1 is in th ...... granzyme A-mediated cell death

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The exonuclease TREX1 is in th ...... granzyme A-mediated cell death

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Bruce Demple

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Dipanjan Chowdhury

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Dong Zhang

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Fred W Perrino

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Jung-Suk Sung

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Paul J Beresford

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Pengcheng Zhu

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scholarly article

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