Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
about
Mitogen-Activated Protein Kinase Kinase 4 Gene Polymorphism and Cancer RiskA docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substratesThe MKK7 gene encodes a group of c-Jun NH2-terminal kinase kinasesRegistered report: Diverse somatic mutation patterns and pathway alterations in human cancersPatterns of somatic mutation in human cancer genomesThe genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroupsp38 mitogen-activated protein kinase-dependent activation of protein phosphatases 1 and 2A inhibits MEK1 and MEK2 activity and collagenase 1 (MMP-1) gene expression.Role of JNK in a Trp53-dependent mouse model of breast cancer.Downregulation of phosphorylated MKK4 is associated with a poor prognosis in colorectal cancer patients.Epigenetics and pancreatic cancer: pathophysiology and novel treatment aspectsAnalysis of the mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer.Molecular signatures of pancreatic cancer.Non-cell-autonomous induction of tissue overgrowth by JNK/Ras cooperation in a Drosophila tumor modelThe Jun kinase 2 isoform is preferentially required for epidermal growth factor-induced transformation of human A549 lung carcinoma cells.Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancerThe mitogen-activated protein kinase kinase 4 has a pro-oncogenic role in skin cancer.Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing.Molecular characteristics of pancreatic ductal adenocarcinomaTwo Distinct Categories of Focal Deletions in Cancer Genomes.Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs.Autophagy regulation in cancer development and therapy.Urokinase receptor and fibronectin regulate the ERK(MAPK) to p38(MAPK) activity ratios that determine carcinoma cell proliferation or dormancy in vivo.Genetic progression and divergence in pancreatic carcinomaHuman gastric cancer kinase profile and prognostic significance of MKK4 kinase.Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells.Suppression of Ras-stimulated transformation by the JNK signal transduction pathwayPathobiology of brain metastases.The association between -1304T>G polymorphism in the promoter of mitogen-activated protein kinase kinase 4 gene and the risk of cervical cancer in Chinese populationJNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.Recurrent MLK4 Loss-of-Function Mutations Suppress JNK Signaling to Promote Colon Tumorigenesis.Tumor cell dormancy induced by p38SAPK and ER-stress signaling: an adaptive advantage for metastatic cells?Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell linesCD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations.Genetic and structural variation in the gastric cancer kinome revealed through targeted deep sequencingGenetic variants in fas signaling pathway genes and risk of gastric cancer.Role of p38 MAP Kinase Signal Transduction in Solid TumorsAssociation of genetic variation in mitotic kinases with breast cancer risk.Immunodeficiency in Pancreatic Adenocarcinoma with Diabetes Revealed by Comparative Genomics.Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancerSin3a acts through a multi-gene module to regulate invasion in Drosophila and human tumors.
P2860
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P2860
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@ast
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@en
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@nl
type
label
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@ast
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@en
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@nl
prefLabel
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@ast
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@en
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@nl
P2093
P1433
P1476
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
@en
P2093
B Swedlund
J M Kyriakis
P304
P407
P577
1997-10-01T00:00:00Z