Molecular cloning, expression, and characterization of a fifth melanocortin receptor
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Contribution of melanocortin receptor exoloops to Agouti-related protein bindingLinkage and association studies between the melanocortin receptors 4 and 5 genes and obesity-related phenotypes in the Québec Family StudyLiver-specific expression of the agouti gene in transgenic mice promotes liver carcinogenesis in the absence of obesity and diabetesMelanocortin 1 Receptor: Structure, Function, and RegulationFunctional characterization of mutations in melanocortin-4 receptor associated with human obesityMelanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5The Melanocortin Receptor System: A Target for Multiple Degenerative DiseasesFluorescence study of conformational properties of melanotropins labeled with aminobenzoic acid.Melanocortin receptor-mediated mobilization of intracellular free calcium in HEK293 cells.Structure-activity relationship and metabolic stability studies of backbone cyclization and N-methylation of melanocortin peptidesMultiple N-methylation of MT-II backbone amide bonds leads to melanocortin receptor subtype hMC1R selectivity: pharmacological and conformational studies.Identification of candidate genes for dyslexia susceptibility on chromosome 18.The yellow mouse obesity syndrome and mechanisms of agouti-induced obesity.Melanocortin-3 receptors and metabolic homeostasis.Conformational study on cyclic melanocortin ligands and new insight into their binding mode at the MC4 receptor.Synthesis, biophysical, and pharmacological evaluation of the melanocortin agonist AST3-88: modifications of peptide backbone at Trp 7 position lead to a potent, selective, and stable ligand of the melanocortin 4 receptor (MC4R).Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position.Relevance of the C-terminal Arg-Phe sequence in gamma(2)-melanocyte-stimulating hormone (gamma(2)-MSH) for inducing cardiovascular effects in conscious rats.Identification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs).Recent developments in our understanding of melanocortin system in the regulation of food intake.Discovery of a β-Hairpin Octapeptide, c[Pro-Arg-Phe-Phe-Dap-Ala-Phe-DPro], Mimetic of Agouti-Related Protein(87-132) [AGRP(87-132)] with Equipotent Mouse Melanocortin-4 Receptor (mMC4R) Antagonist Pharmacology.Plasma neuropeptide Y (NPY) and alpha-melanocyte stimulating hormone (a-MSH) levels in patients with or without hypertension and/or obesity: a pilot study.A Macrocyclic Agouti-Related Protein/[Nle4,DPhe7]α-Melanocyte Stimulating Hormone Chimeric Scaffold Produces Subnanomolar Melanocortin Receptor Ligands.Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2.Adrenocorticotropic hormone enhances the masculinity of an electric communication signal by modulating the waveform and timing of action potentials within individual cellsAn unusual conformation of γ-melanocyte-stimulating hormone analogues leads to a selective human melanocortin 1 receptor antagonist for targeting melanoma cells.Curbing Inflammation through Endogenous Pathways: Focus on Melanocortin PeptidesNeural melanocortin receptors in obesity and related metabolic disorders.Design and microwave-assisted synthesis of novel macrocyclic peptides active at melanocortin receptors: discovery of potent and selective hMC5R receptor antagonists.Phase-dependent resetting of the adrenal clock by ACTH in vitro.Alan [corrected] N. Epstein award: Intracellular signaling and ingestive behaviorsStructure, function and regulation of the melanocortin receptors.Effects of melanocortins on fetal development.Intracellular signaling mechanisms of the melanocortin receptors: current state of the art.Pro-Opiomelanocortin (POMC) Neurones, POMC-Derived Peptides, Melanocortin Receptors and Obesity: How Understanding of this System has Changed Over the Last Decade.ACTH Receptor (MC2R) Specificity: What Do We Know About Underlying Molecular Mechanisms?A fragment of the Escherichia coli ClpB heat-shock protein is a micromolar melanocortin 1 receptor agonist.Molecular identification of the human melanocortin-2 receptor responsible for ligand binding and signaling.Key amino acid residues in the melanocortin-4 receptor for nonpeptide THIQ specific binding and signaling.Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.
P2860
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P2860
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@ast
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@en
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@nl
type
label
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@ast
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@en
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@nl
prefLabel
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@ast
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@en
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@nl
P2093
P3181
P356
P1476
Molecular cloning, expression, and characterization of a fifth melanocortin receptor
@en
P2093
P304
P3181
P356
10.1006/BBRC.1994.1580
P407
P577
1994-05-16T00:00:00Z