WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation - Test2 - elhamkhani - TriplyDB

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation

http://www.wikidata.org/entity/Q28255707

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Wilms tumor 1 mutations in the pathogenesis of acute myeloid leukemia Physiological and pathological implications of 5-hydroxymethylcytosine in diseases Hypoxia, Epithelial-Mesenchymal Transition, and TET-Mediated Epigenetic Changes Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance Functions of TET Proteins in Hematopoietic Transformation The Mechanisms of Generation, Recognition, and Erasure of DNA 5-Methylcytosine and Thymine Oxidations The TET2 interactors and their links to hematological malignancies Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications Role of TET enzymes in DNA methylation, development, and cancer SIRT2 activates G6PD to enhance NADPH production and promote leukaemia cell proliferation HSPB1 Enhances SIRT2-Mediated G6PD Activation and Promotes Glioma Cell Proliferation MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma Epigenetics in normal and malignant hematopoiesis: An overview and update 2017.The genetics of myelodysplastic syndrome: from clonal haematopoiesis to secondary leukaemia Molecular therapy for acute myeloid leukaemia.Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.DNA methylation and hydroxymethylation in hematologic differentiation and transformation.Targeting EZH2 and PRC2 dependence as novel anticancer therapy.Epigenetics, TET proteins, and hypoxia in epithelial-mesenchymal transition and tumorigenesis Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms.Effects of intracerebral hemorrhage on 5-hydroxymethylcytosine modification in mouse brains.Non-catalytic roles for TET1 protein negatively regulating neuronal differentiation through srGAP3 in neuroblastoma cells.Acetate functions as an epigenetic metabolite to promote lipid synthesis under hypoxia.DNA hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy.Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility.DNA methylation profiles in cancer diagnosis and therapeutics.The Methylcytosine Dioxygenase Ten-Eleven Translocase-2 (tet2) Enables Elevated GnRH Gene Expression and Maintenance of Male Reproductive Function.Genetic and epigenetic heterogeneity in acute myeloid leukemia.H3K27 Methylation: A Focal Point of Epigenetic Deregulation in Cancer.Structure and Function of TET Enzymes.A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome.Alternative roles for oxidized mCs and TETs.TET2 in Normal and Malignant Hematopoiesis.TET Methylcytosine Oxidases in T Cell and B Cell Development and Function.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.Synthetic essentiality: Targeting tumor suppressor deficiencies in cancer.Mutant IDH: a targetable driver of leukemic phenotypes linking metabolism, epigenetics and transcriptional regulation.Prognostic role of TET2 deficiency in myelodysplastic syndromes: A meta-analysis.Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma.Pharmacologic Targeting of Chromatin Modulators As Therapeutics of Acute Myeloid Leukemia

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P2860

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation

http://www.wikidata.org/entity/Q28255707

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

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2015年論文

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2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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J.MOLCEL.2014.12.023

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WT1 recruits TET2 to regulate ...... ss leukemia cell proliferation

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Bo Jiao

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Dan Ye

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Huaipeng Lin

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Hui Yang

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Kun-Liang Guan

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Lei Lv

http://www.w3.org/2001/XMLSchema#string

Leilei Chen

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Mengtao Xiao

http://www.w3.org/2001/XMLSchema#string

Pu Wang

http://www.w3.org/2001/XMLSchema#string

Ruibao Ren

http://www.w3.org/2001/XMLSchema#string

P2860

TET2 promotes histone O-GlcNAcylation during gene transcription

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression

The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

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scholarly article

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10.1016/J.MOLCEL.2014.12.023

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4

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2015-02-19T00:00:00Z

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25601757

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Tet methylcytosine dioxygenase 2

Wilms tumor protein homolog

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4336627

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