On the road to immortality: hTERT upregulation in cancer cells
about
Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer ConsortiumLung cancer susceptibility locus at 5p15.33TERT promoter mutations in thyroid cancerSilencing of the hTERT gene by shRNA inhibits colon cancer SW480 cell growth in vitro and in vivoPPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.n-Butylidenephthalide induced apoptosis in the A549 human lung adenocarcinoma cell line by coupled down-regulation of AP-2alpha and telomerase activity.Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivoCumulative effect of multiple loci on genetic susceptibility to familial lung cancer.The use of transformed IMR90 cell model to identify the potential extra-telomeric effects of hTERT in cell migration and DNA damage responseInduction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.Gene therapy in pancreatic cancer.Gene expression levels of human shelterin complex and shelterin-associated factors regulated by the topoisomerase II inhibitors doxorubicin and etoposide in human cultured cells.Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung.Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells.MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity.Inhibition of hTERT/telomerase contributes to the antitumor activity of pristimerin in pancreatic ductal adenocarcinoma cells.ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.Predictors of outcome in an AIEOP series of childhood ependymomas: a multifactorial analysisETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.TGF-beta and cancer: is Smad3 a repressor of hTERT gene?Inhibition of cell proliferation and induction of apoptosis by oleanane triterpenoid (CDDO-Me) in pancreatic cancer cells is associated with the suppression of hTERT gene expression and its telomerase activityTelomerase reverse transcriptase (TERT) is a therapeutic target of oleanane triterpenoid CDDO-Me in prostate cancerInhibition of telomerase activity by oleanane triterpenoid CDDO-Me in pancreatic cancer cells is ROS-dependent.Latent membrane protein 1 of Epstein-Barr virus activates the hTERT promoter and enhances telomerase activity in B lymphocytes.Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition.Chromatin and epigenetic regulation of the telomerase reverse transcriptase gene.Histone deacetylase inhibition as an anticancer telomerase-targeting strategy.Krüppel-like factor 2 represses transcription of the telomerase catalytic subunit human telomerase reverse transcriptase (hTERT) in human T cells.Effect of vector-expressed shRNAs on hTERT expression.Quantitative assessment of common genetic variants on chromosome 5p15 and lung cancer risk.The Clinical Implications of Human Telomerase Reverse Transcriptase Expression in Grade and Prognosis of Gliomas: a Systematic Review and Meta-analysis.Antitumor effect of new multiple antigen peptide based on HLA-A0201-restricted CTL epitopes of human telomerase reverse transcriptase (hTERT).Telomerase Induction in HPV Infection and Oncogenesis.Telomerase promotes efficient cell cycle kinetics and confers growth advantage to telomerase-negative transformed human cells.Downregulation of human telomerase reverse transcriptase through anti-C-myc siRNA in human colon cancer Colo 320 cells.siRNA directed against c-Myc inhibits proliferation and downregulates human telomerase reverse transcriptase in human colon cancer Colo 320 cells.Multistep regulation of telomerase during differentiation of HL60 cells.Photochemically enhanced delivery of a cell-penetrating peptide nucleic acid conjugate targeting human telomerase reverse transcriptase: effects on telomere status and proliferative potential of human prostate cancer cells.The tumor suppressor activity induced by adenovirus-mediated BRCA1 overexpression is not restricted to breast cancers.Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors.
P2860
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P2860
On the road to immortality: hTERT upregulation in cancer cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
On the road to immortality: hTERT upregulation in cancer cells
@ast
On the road to immortality: hTERT upregulation in cancer cells
@en
On the road to immortality: hTERT upregulation in cancer cells
@nl
type
label
On the road to immortality: hTERT upregulation in cancer cells
@ast
On the road to immortality: hTERT upregulation in cancer cells
@en
On the road to immortality: hTERT upregulation in cancer cells
@nl
prefLabel
On the road to immortality: hTERT upregulation in cancer cells
@ast
On the road to immortality: hTERT upregulation in cancer cells
@en
On the road to immortality: hTERT upregulation in cancer cells
@nl
P1433
P1476
On the road to immortality: hTERT upregulation in cancer cells
@en
P2093
Ralf Janknecht
P356
10.1016/S0014-5793(04)00356-4
P407
P577
2004-04-23T00:00:00Z